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Findings open the way to more precise diagnoses and treatments of Alzheimer’s disease: Why some cases result in rapid decline and death

An international team lead by Case Western Reserve University’s School of Medicine has made a significant breakthrough in understanding why Alzheimer’s disease progresses so rapidly in some people that they die within three years. The researchers found a link between strains of misshapen and fast-replicating tau protein and accelerated cognitive decline — a critical result […]

Is energy the key to Alzheimer’s disease?

A team of researchers at the University of Adelaide has found a link between the way that cells produce energy for brain function and the mutated genes found in Alzheimer’s disease. The discovery published in Disease Models and Mechanisms has prompted further examination of the link as a fundamental, early driver of Alzheimer’s disease in […]

New type of earthquake discovered

A Canadian-German research team have documented a new type of earthquake in an injection environment in British Columbia, Canada. Unlike conventional earthquakes of the same magnitude, they are slower and last longer. The events are a new type of induced earthquake that have been triggered by hydraulic fracturing, a method used in western Canada for […]

Bringing 400-million-year-old fossilized armored worms to ‘virtual’ life

An international team of scientists from the United States and Australia, led by Sarah Jacquet at the University of Missouri, has documented the discovery of two new species of fossilized armored worms in Australia — Lepidocoleus caliburnus and Lepidocoleus shurikenus — dating from about 400 million years ago. Then, using the micro-CT imaging capabilities of […]

Are Nurse Staffing Agencies Overcharging Hospitals?

A group of U.S. senators and representatives penned a letter to the COVID-19 Response Team and other agencies on Wednesday, urging them to investigate allegations of overpricing by nurse staffing agencies relied on to fill gaps in hospital staffing during the pandemic. In the letter, Sens. Mark Kelly (D-Ariz.) and Bill Cassidy, MD (R-La.), and […]

Artificial intelligence successfully predicts protein interactions: Research could lead to a wealth of drug targets

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions. The study, published in Science, identified more than 100 probable protein complexes for the first time and provided structural models for more than 700 previously uncharacterized ones. Insights […]

When macrophages let off steam: Changes in cell metabolism protect macrophages from overloading and thus assist the resolution of inflammatory reactions

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages. Danger signals released by damaged cells during inflammation play a role during this process. ‘Rewiring’ the mitochondria in the macrophages protects them against overloading and can thus improve the way in […]

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