Bariatric Surgery Tied to Long-Term Cognitive Benefits
Gastric bypass surgery in people with severe obesity was associated with sustained improvements in cognitive function, inflammation, and comorbidities, according to results of a cohort study in the Netherlands. At 2 years post-surgery, neuropsychological tests showed improvements of 20% or higher in global cognition (43% of patients), ability to shift attention (40%), episodic memory (32%), […]
Novel Chemo Delivery System Achieves High Response Rate in Bladder Cancer
CHICAGO — An investigational intravesical delivery system designed to provide sustained local release of gemcitabine into the bladder produced high rates of complete response (CR) in difficult-to-treat non-muscle-invasive bladder cancer (NMIBC), data from an ongoing phase IIb study showed. Preliminary results from the SunRISe-1 trial demonstrated that monotherapy with the novel treatment, dubbed TAR-200, led […]
Testosterone Tied to Sustained Weight Loss in Men With Hypogonadism and Obesity
SAN DIEGO — Long-term testosterone therapy was associated with sustained reductions in weight for men with hypogonadism and class III obesity, a researcher reported. In registry data on 76 patients, those who opted to receive testosterone undecanoate experienced a 26% reduction in their body mass index (BMI) over close to a decade of follow-up, reported […]
‘Senolytic’ Therapy Shows Promise in Neovascular Eye Disease
NEW YORK CITY — An investigational drug targeting senescent cells achieved sustained improvement in visual acuity in patients with diabetic macular edema (DME) or neovascular age-related macular degeneration (AMD), a small pilot study showed. After single doses of UBX1325, four of eight evaluable patients with advanced DME had at least 10 letters of improvement in […]
Choline during pregnancy impacts children’s sustained attention
Seven-year-old children performed better on a challenging task requiring sustained attention if their mothers consumed twice the recommended amount of choline during their pregnancy, a new Cornell study has found. The study, which compared these children with those whose mothers had consumed the recommended amount of choline, suggests that the recommended choline intake for expectant […]
Preventing the long-term effects of traumatic brain injury: New study points to a potential new treatment that could prevent chronic complications
You’ve been in a car accident and sustained a head injury. You recovered, but years later you begin having difficulty sleeping. You also become very sensitive to noise and bright lights, and find it hard to carry out your daily activities, or perform well at your job. This is a common situation after a traumatic […]