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The feeling of hunger itself may slow aging in flies

From low-carb to intermittent fasting, surgery to Ozempic — people turn to a seemingly never-ending array of diets, procedures and drugs to lose weight. While it has been long understood that limiting the amount of food eaten can promote healthy aging in a wide range of animals, including humans, a new study from University of […]

Bariatric Surgery May Eliminate Obesity-Related Breast Cancer Risk

Bariatric surgery for women with obesity was associated with a reduction in breast cancer risk that reached levels seen among those with a normal body mass index (BMI), researchers have found. In their retrospective study of almost 70,000 women, an increased risk for incident breast cancer was observed in women who did not undergo bariatric […]

Obesity treatment could offer dramatic weight loss without surgery or nausea

Imagine getting the benefits of gastric bypass surgery without going under the knife — a new class of compounds could do just that. In lab animals, these potential treatments reduce weight dramatically and lower blood glucose. The injectable compounds also avoid the side effects of nausea and vomiting that are common with current weight-loss and […]

RT After Breast-Conserving Surgery Shows No Survival Advantage Decades Later

Radiotherapy after breast-conserving surgery for early breast cancer substantially reduced the risk of disease recurrence, yet the benefit did not translate to an improvement in overall survival (OS) at 30 years, a long-term analysis of the Scottish breast conservation trial showed. Compared with no radiotherapy, adjuvant locoregional radiotherapy reduced the risk of ipsilateral breast tumor […]

Bariatric Surgery Cuts All-Cause Mortality Rate Over Many Years

SAN DIEGO –Patients who underwent bariatric surgery saw a reduction in all-cause mortality that held strong over multiple years, researchers reported. In a retrospectives study, bariatric surgery patients were 16% less likely to die from any cause than their matched non-surgical counterparts over a median 13.2 follow-up period (hazard ratio 0.84, 95% CI 0.79-0.90, P<0.001), […]

Study Suggests Potential to Skip Surgery for Selected Breast Cancer Patients

Women who chose not to have surgery after a pathologic complete response (pCR) to neoadjuvant therapy for early HER2-positive or triple-negative breast cancer (TNBC) had no recurrences during the first 2 years of follow-up, a small prospective study showed. Overall, 31 of 50 (62%) women had no evidence of residual disease by image-guided vacuum-assisted core […]

Oxygen Concentration During Surgery: No Help for Post-Op Nausea, Vomiting

NEW ORLEANS — There was no benefit to giving patients supplemental oxygen during surgery to reduce postoperative nausea and vomiting (PONV), according to a post hoc analysis of a randomized trial. The multiple cross-over cluster trial had eight isolated operating rooms randomized to alternate between 80% versus 30% fractions of inspired oxygen every 2 weeks […]

Bariatric Surgery Ups Epilepsy Risk

Bariatric surgery increased the risk of epilepsy, a retrospective Canadian study showed. Over a minimum of 3 years follow-up, bariatric surgery patients had a 45% increased risk of developing epilepsy compared with people who did not have bariatric surgery (HR 1.45, 95% CI 1.35-1.56), reported Jorge Burneo, MD, MSPH, of Western University in London, Ontario, […]

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