Targeting New Pathways to Improve Outcomes in Renal Cell Carcinoma
NASHVILLE, Tenn. — Building on the existing immune checkpoint inhibitor (ICI) platform, new treatment strategies for renal cell carcinoma (RCC) seek to adapt the cancer’s immunity cycle to inform development of more effective therapies, according to a review presented here. Limited options exist beyond anti-VEGF and ICI-based strategies for patients with advanced disease, particularly those […]
Nursing Leaders Tackle Ways to Fix ‘Accelerated Burnout’ in New Nurses
Nursing leaders shared strategies for addressing “accelerated burnout” among nurses new to the profession during a panel discussion hosted by the National Council of State Boards of Nursing (NCSBN) on Thursday. Approximately 100,000 RNs left the workforce during the COVID-19 pandemic and another 800,000 anticipate leaving in the next 5 years, said Maryann Alexander, PhD, […]
Helmet CPAP Leads Noninvasive Ventilation Therapies for Acute Respiratory Failure
The available noninvasive oxygenation strategies varied in their effectiveness in treating acute hypoxemic respiratory failure (AHRF), according to a meta-analysis of randomized trials. Helmet continuous positive airway pressure (CPAP) was the only modality that had at least moderate certainty evidence backing a probable mortality reduction compared with standard oxygen therapy (SOT; 231 fewer deaths per […]
Engaging in Healthcare May Close Longevity Gap Between Black and White Men With HIV
WASHINGTON — For men who have sex with men and are living with HIV, adopting strategies that would further engage Black men with the healthcare system could potentially close the gap in longevity between Black and white men, researchers suggested here. Using the framework of the HIV Care Continuum, simulation modeling showed that engagement with […]
Lancet Commission Calls for Ending Stigma, Discrimination Around Mental Health
Evidence-based strategies should be implemented to eliminate the stigma and discrimination around mental health conditions, according to an extensive report from The Lancet Commission. The Commission’s recommendations are intended for a broad cross section of stakeholders, including governments, international organizations, schools, public and private employers, and healthcare workers and their organizations, noted co-chair Graham Thornicroft, […]