Hundreds of injured singers profiled: Analysis identifies most common conditions and treatments
An analysis of more than 400 singers who sought treatment at UT Southwestern Medical Center for vocal injuries provides a wealth of data on a topic that’s often considered taboo to discuss in the singing community. The findings, published in The Laryngoscope, show that only 1 in 7 subsequently needed surgery for injuries that weren’t […]
Artificial intelligence successfully predicts protein interactions: Research could lead to a wealth of drug targets
UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions. The study, published in Science, identified more than 100 probable protein complexes for the first time and provided structural models for more than 700 previously uncharacterized ones. Insights […]
Potential strategy for fighting obesity: Lab safely replicates weight-loss benefits of plant linked to harmful side effects
UT Southwestern scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that — despite its harmful side effects — hold critical answers to developing therapies for obesity. Celastrol, derived from the root extracts of a white-flowered plant in China, has drawn increased attention in recent years after studies […]
Gene for sex hormone synthesis could play key role in eczema: Potential new treatment target for common skin condition
A study led by UT Southwestern dermatologists suggests that a common inflammatory skin condition may stem from poorly regulated sex hormones. The finding, published this week in PNAS, could offer an unexpected new target to fight this condition. Atopic dermatitis (AD) is a form of eczema. AD affects up to 13% of children and 10% […]
Common weight-loss drug successfully targets fat that can endanger heart health
Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide. In adults who are overweight or have obesity combined with high cardiovascular risk, once-daily liraglutide combined with lifestyle interventions significantly lowered two types of fat that have been associated with risk to heart health: visceral fat […]
Researchers find immune component to rare neurodegenerative disease: Niemann-Pick disease type C, long thought to be tied to cholesterol metabolism, may eventually be treated with immune inhibitors
UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C. The finding, made in mouse models and published online in Nature, could offer a powerful new therapeutic target for Niemann-Pick disease type C, a condition that was identified more than a century ago but still […]