Big Changes to ACA Unlikely During Current Congress, Expert Suggests
Republicans likely will be successful in blocking any significant expansion of the Affordable Care Act (ACA), former Health and Human Services official Thomas Barker, JD, predicted at an event hosted by the Alliance for Health Policy on the future of the ACA. “It’s hard for me to see how, for example, a public option can […]
Havana Syndrome Mystery Continues to Deepen
Despite persistent symptoms, no significant evidence of brain injury and no abnormalities in most clinical measures were found in U.S. government personnel who experienced anomalous health incidents (AHIs) known as Havana syndrome, NIH researchers said. After adjusting for multiple comparisons, no differences in MRI measures of brain structure or function emerged between individuals with AHIs […]
Most People With TB Report No Persistent Cough
A significant proportion of people in the community with pulmonary tuberculosis (TB) have subclinical disease, according to a meta-analysis involving survey studies across Africa and Asia. In adjusted analyses, 82.8% (95% CI 78.6-86.6) of participants with TB reported no persistent cough and 62.5% (95% CI 56.6-68.7) reported no cough at all, according to Frank Cobelens, […]
Investigational Agent Shows Benefit in Myasthenia Gravis
The investigational monoclonal antibody batoclimab led to significant improvement in activities of daily living in people with generalized myasthenia gravis (gMG), a multicenter phase III trial found. The rate of sustained improvement on Myasthenia Gravis Activities of Daily Living (MG-ADL) scores for antibody-positive patients in the first treatment cycle was 58.2% in the batoclimab group […]
Study identifies multi-organ response to seven days without food
New findings reveal that the body undergoes significant, systematic changes across multiple organs during prolonged periods of fasting. The results demonstrate evidence of health benefits beyond weight loss, but also show that any potentially health-altering changes appear to occur only after three days without food. The study, published today in Nature Metabolism, advances our understanding […]
PROs for Cutaneous Chronic GVHD After Transplant Tied to Disease Severity, Mortality
Skin-involved chronic graft-versus-host disease (cGVHD) had a significant association with long-term impairment of patient-reported outcomes (PROs), which also had a prognostic association with mortality, a multicenter prospective study showed. Patients with sclerotic cGVHD had significantly worse scores on a validated quality-of-life (QOL) instrument compared with those who had epidermal-type cGVHD. Patients with combination GVHD subtypes […]
Small Decline Seen in Ob/Gyn Residency Applications in Abortion Ban States
In the first residency application cycle after Roe v. Wade was overturned, there was a small but significant decrease in the percentage of applicants to ob/gyn programs in states with abortion restrictions compared with previous years, Electronic Residency Application Service (ERAS) data showed. For the 2023 cycle, there were 2,463 ob/gyn applicants, 85.4% of whom […]
Tebentafusp’s OS Benefit in Uveal Melanoma Holds Up at 3 Years
MADRID — The significant survival benefit with the bispecific T-cell receptor therapy tebentafusp (Kimmtrak) held up at 3 years for selected patients with previously untreated metastatic uveal melanoma, updated results of a phase III trial demonstrated. In HLA-A*02:01-positive patients, landmark analyses showed improved overall survival (OS) at 1, 2, and 3 years with tebentafusp versus […]
Reduced Mortality Seen in Cancer Survivors Who Meet Exercise Guidelines
Exercise consistent with national guidelines was associated with a significant reduction in all-cause mortality in long-term cancer survivors, a pan-cancer analysis showed. In a study involving 11,480 survivors, guideline-concordant exercise was associated with a 25% reduced risk of all-cause mortality compared with no exercise (HR 0.75, 95% CI 0.70-0.80) at a median follow-up of 16 […]
A new breakthrough in obesity research may allow you to lose fat while eating all you want
This is a significant development that brings hope to the one billion individuals with obesity worldwide. Researchers led by Director C. Justin LEE from the Center for Cognition and Sociality (CCS) within the Institute for Basic Science (IBS) have discovered new insights into the regulation of fat metabolism. The focus of their study lies within […]