Weight-Loss Drug Zepbound Faces Supply Issues
Another popular weight-loss drug is in short supply. Doses of tirzepatide (Zepbound) are few and far between, experts told MedPage Today, although the injectable has not been listed in the FDA Drug Shortage Database as of today. Another version of tirzepatide, for type 2 diabetes (Mounjaro), has been on the FDA shortage list since December […]
Inhaled Antibiotic Cuts Risk of Ventilator-Associated Pneumonia
A short course of an inhaled antibiotic helped prevent the incidence of ventilator-associated pneumonia in the intensive care unit (ICU), a randomized trial in France showed. In critically ill patients intubated for between 3 to 4 days, administration of amikacin (Arikayce) reduced the rate of first ventilator-associated pneumonia compared with an inhaled placebo (15% vs […]
Early treatment of child obesity is effective
The early treatment of obesity in children is effective in both the short and long term, researchers from Karolinska Institutet report in a study published in The International Journal of Obesity. The researchers followed over 170 young children in Sweden who had received treatment for diagnosed obesity. The children were recruited to the randomised controlled […]
Are You In A ‘Permacrisis?’ Here’s How To Tell.
Collins Dictionary named “permacrisis” the word of the year for 2022. In short, it means “an extended period of instability and insecurity.” After all we’ve gone through this year — COVID variants, mass shootings, the war in Ukraine and more — you probably find that definition relatable. You may have experienced hopelessness, anxiety, loneliness, grief […]
Do You Get More Anxious Or Sad In The Fall? There’s A Reason For That.
When we talk about seasonal depression, the short, frosty days of winter probably come to mind. After all, the bulk of people who experience seasonal mood changes feel the most stress and anxiety during the thick of winter. But seasonal affective disorder can happen at any time, in any season. And right now, as we […]
PCOS Pain Caused Kelly Ripa to Pass Out During Sex
In an upcoming memoir, Live Wire: Long-Winded Short Stories, daytime talk-show host Kelly Ripa shares a story that has many people talking. The story, outlined in Haute Living, is in a chapter entitled “Don’t Let Your Husband Pick Your Death Clothes.” As Ripa related, in 1997 as a new mother she passed out during sex […]
Sacral Neuromodulation Promising in Neurogenic Lower Urinary Dysfunction
Sacral neuromodulation (SNM) is effective — at least in the short term — for patients with a type of urinary tract dysfunction, according to Swiss investigators. In a sham-controlled, double-blind study, 60 eligible patients with neurogenic lower urinary tract dysfunction (NLUTD) — i.e., with urgency frequency syndrome, urgency incontinence, or chronic urinary retention — had […]
Demand Rising for ‘Bootlegged’ Weight-Loss Drug
Novo Nordisk’s weight management drug semaglutide (Wegovy) has been in prolonged short supply due to “unprecedented demand,” prompting increased — and questionable — interest in compounded formulations of the drug, physicians said. Endocrinologists and obesity medicine specialists have been sounding the alarm about what they say amounts to bootleg semaglutide, concerned about safety and quality […]
No Early Cardiovascular Risks With Testosterone Treatment
Testosterone treatment for hypogonadism did not increase short- or medium-term risks for cardiovascular events, according to a systematic review and meta-analysis. Cardiovascular risks were similar between men in the testosterone group and those in the placebo group (7.5% vs 7.2%; OR 1.07, 95% CI 0.81-1.42, P=0.62), reported Channa Jayasena, PhD, of Imperial College London, at […]
Mixed Results With RT Plus Short-Term ADT in Intermediate-Risk Prostate Cancer
CHICAGO — Adding a short course of androgen deprivation therapy (ADT) to dose-escalated radiotherapy (RT) led to a mixed bag of outcomes in intermediate-risk prostate cancer, according to a large randomized trial. The addition of 6 months of ADT did not improve overall survival (OS) compared with RT alone, but the hormonal therapy was associated […]