Tailoring Drug Interaction Alerts to the ICU Reduced Number of High-Risk Combos
PHOENIX — Tailoring potential drug-drug interaction (DDI) alerts to the intensive care unit (ICU) setting significantly reduced the number of administered high-risk drug combinations, a cluster randomized stepped-wedge trial showed. Among nearly 10,000 patients admitted to the ICU, the use of potential DDI alerts tailored to the ICU led to a 12% decrease (95% CI […]
Low Tidal Volume Compliance Still Lacking in Mechanical Ventilation
Implementation of a well-established protective ventilation setting was limited in practice in the U.S. and U.K., electronic health records showed. From the records of mechanically ventilated people, median tidal volume was 7.48 mL/kg of predicted body weight in a U.K. database and 7.91 mL/kg in the U.S., both approaching the accepted upper limit of <8 […]
These Surgeries Made the Sharpest Turns to Outpatient Setting After COVID
Some common general surgeries had the biggest migrations to the outpatient setting during the first year of the COVID-19 pandemic, a retrospective cohort study confirmed. Compared with the previous few years, calendar year 2020 saw disproportionately more outpatient cases of mastectomy for cancer, minimally invasive adrenalectomy, thyroid lobectomy, breast lumpectomy, minimally invasive ventral hernia repair, […]
7 Boundaries Adult Children Should Consider Setting With Their Parents
Setting boundaries with your parents as an adult isn’t always easy. But it may be necessary for your own well-being and the health of the relationship. Know that boundaries are for you. They’re a way to respect yourself and honor your needs. They’re not about controlling other people — in this case, your parents. Advertisement […]
Sugar disrupts microbiome, eliminates protection against obesity and diabetes
A study of mice found that dietary sugar alters the gut microbiome, setting off a chain of events that leads to metabolic disease, pre-diabetes, and weight gain. The findings, published today in Cell, suggest that diet matters, but an optimal microbiome is equally important for the prevention of metabolic syndrome, diabetes, and obesity. Diet alters […]
Pre-Op Atezolizumab Promising in Muscle-Invasive Bladder Cancer
The use of a checkpoint inhibitor combined with chemotherapy in the neoadjuvant setting appeared to be effective for patients with muscle-invasive bladder cancer (MIBC), according to results from a phase II trial. Among 39 patients, the addition of the PD-L1 inhibitor atezolizumab (Tecentriq) to gemcitabine and cisplatin resulted in a non-muscle-invasive downstaging rate of 69% […]
Picture warnings on sodas? A promising tool to fight childhood obesity: Study conducted in ‘mini mart’ laboratory setting shows parents less likely to choose sugary drinks with health warnings
A study published in the journal PLOS Medicine is the first to examine in a realistic setting whether pictorial health warnings on sugary drinks — like juice and soda — influence which beverages parents buy for their children. The findings are promising: The warnings reduced parental purchases of sugary drinks for their kids by 17%. […]