Certain SSRIs May Increase Arrhythmia Risk in Select Patients
Therapeutic doses of some selective serotonin reuptake inhibitors (SSRIs) may lead to cardiotoxic concentration levels associated with increased risk of arrhythmia in certain groups of patients, including those 65 and up, according to a Norwegian cohort study. In patients 65 and over taking escitalopram (Lexapro) daily, about 20% were predicted to reach potentially pro-arrhythmic concentrations […]
Another Online SARMs Retailer Gets a Warning From the FDA
The FDA issued a warning letter to an online retailer selling multiple selective androgen receptor modulators (SARMs) earlier this month, in an ongoing effort to curb their use in consumers, the agency said. This recent letter advised a California-based company, known as Warrior Labz SARMS, and its owner, Jeremy Brown, to stop actively marketing SARMs […]
Oral Drug Shows Benefit for Notalgia Paresthetica in Mid-Stage Trial
A selective kappa opioid receptor agonist in patients with notalgia paresthetica led to “modestly” greater improvements in itchiness over placebo, but was associated with adverse events, a randomized phase II trial showed. At 8 weeks, improvements in average itchiness was significantly greater with oral difelikefalin (Korsuva) versus placebo on the Worst Itch Numeric Rating Scale […]
Microbes can degrade the toughest PFAS: Under anaerobic conditions, common microbial communities can break the ultra-strong carbon-fluorine bond
Engineers at UC Riverside are the first to report selective breakdown of a particularly stubborn class of PFAS called fluorinated carboxylic acids (FCAs) by common microorganisms. Under anaerobic conditions, a carbon-carbon double bond is crucial for the shattering the ultra-strong carbon-fluorine bond by microbial communities. While breaking the carbon-carbon bond does not completely degrade the […]
What Are the Six Types of Anxiety Disorders? 6 Ways to Treat
The six main types of anxiety disorders are: A typical variant is selective mutism, which may be often seen in kids who are confident in front of their family but may not speak at all in school or other places. Generalized anxiety disorder (GAD): It is a long-term disorder that makes a person inappropriately anxious […]