Pritzker signs bill to strengthen safe public drinking water
A new law signed Monday seeks to strengthen safe drinking water standards.
Most Moms Knew About Safe Sleep for Infants, But Still Engaged in Unsafe Practices
Despite knowledge of and intention to follow safe sleep guidelines for infants, mothers often engaged in non-recommended sleep practices, a series of small focus groups and surveys showed. Among 25 mothers, 80% reported holding or rocking their infant to sleep, and 76% reported feeding their infant to sleep, Lara McKenzie, PhD, MA, of Nationwide Children’s […]
COVID-19 Booster Shots Can Wait
Vaccines against SARS-CoV-2 are proving quite safe and highly effective in the prevention of COVID-19, especially severe and/or fatal disease. Over half of the U.S. population has initiated immunization and more than three out of four people in the U.S. over the age of 65 have completed vaccination. The promising vaccine roll-out and reductions in […]
Novel Oral Antibiotic Effective Against Uncomplicated UTIs
Gepotidacin — a first-in-class oral antibiotic — appeared effective and safe for the treatment of uncomplicated urinary tract infections (UTIs) in a pair of large, phase III non-inferiority studies. In the two trials — EAGLE-2 and EAGLE-3 — the therapy was shown to be noninferior to nitrofurantoin, an antibiotic commonly used as a first-line therapy […]
Your Heart Has An ‘Age,’ Too. Here Are 7 Ways To Keep It Young.
LOADINGERROR LOADING If you’re reading this, then it’s safe to say that you’re interested in not just learning more about heart health, but also ways to keep your ticker strong for many years to come. While everybody is different, there is an idea that your heart has an age that’s not always correlated with your […]
‘Watch and Wait’ With Small Renal Masses: When and How Should Docs Intervene?
Active surveillance of small renal masses appears to be safe, but if intervention does become necessary, what should trigger it? “We now know that with at least 10 years of data that active surveillance is safe and non-inferior to primary intervention,” said Phillip Pierorazio, MD, of the University of Pennsylvania in Philadelphia, during a presentation […]
Hypofractionated RT for Breast Cancer Post-Mastectomy as Effective as Standard RT
SAN DIEGO — Hypofractionated radiation appeared to be as safe and effective as conventionally fractionated radiation therapy for patients with breast cancer who underwent implant-based breast reconstruction following mastectomy, according to results from the FABREC randomized trial. For the study’s primary outcome of change in physical well-being score, patients in both groups reported similar scores […]
Shorter TB Regimen Misses the Mark
Shorter high-dose rifampicin regimens proved safe for treating pulmonary tuberculosis (TB), but failed to demonstrate noninferiority compared with the standard 6-month regimen, a phase III trial found. For the primary efficacy outcome, an absolute 6.3% more adults receiving a 4-month regimen that included the highest dose of rifampicin had an unfavorable outcome at 12 to […]
Pulsed Field Ablation Measures Up in Head-to-Head Trial
AMSTERDAM — Pulsed field ablation appeared as safe and effective as thermal ablation in treating paroxysmal atrial fibrillation (Afib) in the first randomized head-to-head trial for the novel technology. Efficacy failure of the procedure — initial procedural failure, documented atrial tachyarrhythmia after a 3-month blanking period, antiarrhythmic drug use, cardioversion, or repeat ablation — at […]
Blinatumomab Plus Chemo Effective in Aggressive Infant ALL
Adding a postinduction course of blinatumomab (Blincyto) to chemotherapy appeared safe and highly effective for treating an aggressive form of acute lymphoblastic leukemia (ALL) in infants, according to results from a phase II study. Of the 30 infants with newly diagnosed KMT2A-rearranged ALL, 16 achieved minimal residual disease (MRD)-negative status following the 28-day infusion with […]