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High-fat diets alter gut bacteria, boosting colorectal cancer risk in mice

The prevalence of colorectal cancer in people under the age of 50 has risen in recent decades. One suspected reason: the increasing rate of obesity and high-fat diets. Now, researchers at the Salk Institute and UC San Diego have discovered how high-fat diets can change gut bacteria and alter digestive molecules called bile acids that […]

Prescriptions for Stimulants Jumped During the Pandemic

Prescriptions for stimulants have risen in recent years, with the sharpest increases seen during the pandemic, according to the CDC. In an analysis of claims from employer-sponsored insurance, the percentage of enrollees with one or more prescription stimulant fills rose from 3.6% in 2016 to 4.1% in 2021, Melissa Danielson, MSPH, of the CDC, and […]

Placebo Responses in Migraine Prevention Trials Tick Upward Over Time

Placebo responses in migraine prevention trials appear to have risen over time, a systematic review and meta-analysis showed. A significant increase in placebo response was seen by publication year in migraine prevention studies that involved oral placebo (rho 0.39, P=0.047) but not in studies with injectable placebo (rho -0.07, P=0.724), reported Stewart Tepper, MD, of […]

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