Xeljanz Edges Humira Just a Bit for Real-World RA Patients, Study Suggests
Tofacitinib (Xeljanz) appeared ever-so-slightly more effective than adalimumab (Humira) for rheumatoid arthritis (RA) in a study that used real-world patient data to simulate a randomized head-to-head trial. Leaders of Australia’s OPAL network of rheumatologists reported that, among 699 RA patients starting their first biologic or targeted therapy for the disease, the mean 28-joint Disease Activity […]
Sex and the (Not Quite) Single Arthritis Patient
COPENHAGEN — Half of patients with rheumatoid arthritis (RA) and 30% of those with psoriatic arthritis (PsA) reported substantial problems with sexual function, according to a survey reported here. Among 27 with RA diagnoses, 13 had scores on the 14-item Changes in Sexual Functioning Questionnaire (CSFQ) in the range indicative of sexual dysfunction, said Carlos […]
Is Alzheimer’s Risk Lower With TNF Inhibitors?
Tumor necrosis factor (TNF) inhibitors for rheumatoid arthritis were linked with a lower risk of Alzheimer’s disease and related dementia, but only in people with cardiovascular disease, data from the DREAM (Drug Repurposing for Effective Alzheimer’s Medicines) study showed. Among more than 22,000 older adults, targeted disease-modifying antirheumatic drugs overall were not associated with a […]