Retinal Changes Emerge Years Before Parkinson’s Disease
People with Parkinson’s disease had retinal changes that could be seen with optical coherence tomography (OCT) years before diagnosis, cross-sectional data suggested. Both incident and prevalent Parkinson’s disease were associated with reduced ganglion cell-inner plexiform layer (GCIPL) and inner nuclear layer (INL) thicknesses, reported Siegfried Karl Wagner, MSc, MD, of University College London in England, […]
Pegcetacoplan-Related Eye Inflammation: The Search Is on for Answers
SEATTLE — Reports of unexpected panuveitis and retinal occlusive vascular disease associated with pegcetacoplan (Syfovre) treatment has triggered a search for answers by ophthalmologists and the drug’s manufacturer. Since July 3, the American Society of Retina Specialists (ASRS) Research and Safety in Therapeutics (ReST) Committee has learned of seven cases of retinal inflammation and vascular […]
Retinal OCT Shows Promise as Diagnostic Aid for Mild Cognitive Impairment
Aided by artificial intelligence, analysis of retinal images and related data identified condition-specific features that distinguished patients with mild cognitive impairment from those with normal cognition, a prospective study showed. The analytic model, used to evaluate optical coherence tomography (OCT) and OCT angiography (OCTA), detected changes in the retina and microcirculation that distinguished mild cognitive […]
Intravitreal Methotrexate Reduces Reoperation After Retinal Detachment Repair
NEW YORK CITY — Postoperative intravitreal methotrexate for retinal detachment led to a significant reduction in reoperation and improved visual acuity, a retrospective chart review showed. The absolute difference in reoperation rate was small, greater than 1% without methotrexate versus 0.4% with three to five postoperative injections of the antiproliferative agent, but the difference translated […]