High-fat diets trigger inflammatory immune cell generation in bone: A study suggests that high-fat diets fuel the creation of inflammatory immune cells in the bone marrow of mice.
The results may help explain how high-fat diets trigger inflammation, which can contribute to the development of insulin resistance, type 2 diabetes and other complications in individuals with obesity. An invasion of inflammatory immune cells, called monocytes, into fat tissue is a hallmark of obesity, but what leads to this harmful phenomenon is unclear. Many […]
10-Year Follow-Up Confirms Benefit of Chemoradiotherapy in MIBC Patients
Long-term results confirmed that the benefit of adding chemotherapy to radiotherapy was maintained in patients with muscle-invasive bladder cancer (MIBC) in a follow-up to the phase III randomized BC2001 trial. Over a median follow-up of about 10 years, locoregional control was significantly improved by adding 5-fluorouracil and mitomycin C to radiotherapy, with a 5-year recurrence-free […]
Specific brain responses to traumatic stress linked to PTSD risk
Results from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, individuals facing potentially threatening situations who had less activity in their hippocampus — a brain structure critical for forming memories of situations that are dangerous and that are safe — developed more severe posttraumatic stress […]
Gender bias in search algorithms has effect on users, new study finds: Search results can influence us in ways that reinforce social inequality
Gender-neutral internet searches yield results that nonetheless produce male-dominated output, finds a new study by a team of psychology researchers. Moreover, these search results have an effect on users by promoting gender bias and potentially influencing hiring decisions. The work, which appears in the journal Proceedings of the National Academy of Sciences (PNAS), is among […]
How Does the Non-ADHD Partner feel? 2 Types, 3 Causes, Symptoms
ADHD in adults results in mental and physical problems that may eventually impact their relationships and cause difficulty in their daily routine. Various research has proven that attention deficit hyperactivity disorder (ADHD) is a disorder of executive functioning, which involves five areas of daily behaviors: Time management Organization Motivation Concentration Self-discipline Most couples with undiagnosed […]
Two Drugs Better Than One for ‘Rescue’ Asthma Therapy
SAN FRANCISCO — Phase III results look very good for a two-drug combination inhaler in helping asthma patients regain symptom control when maintenance medications weren’t doing the job. In the MANDALA trial, patients using the investigational product PT027, which combines 90 μg of albuterol with 80 μg of budesonide, were significantly less likely to experience […]
What It’s Like Being an Adult With ADHD? 9 Symptoms, Complications
ADHD in adults results in mental and physical problems that eventually impact relationships and cause difficulty in daily life. Adults with attention deficit hyperactivity disorder (ADHD) might face a wide range of difficulties in all aspects of their lives. According to the American Psychiatric Association, approximately five percent of children have ADHD and roughly half […]
Aducanumab Data Finally Published, but Alzheimer’s Experts Spot Problems
The long-awaited results of the twin phase III trials for aducanumab (Aduhelm), the controversial drug approved last year for early Alzheimer’s disease, were published in the Journal of Prevention of Alzheimer’s Disease (JPAD), a journal whose editor-in-chief is aducanumab researcher and study co-author Paul Aisen, MD, of the University of Southern California in Los Angeles. […]
Mindfulness therapy reduces opioid misuse and chronic pain in primary care, according to new research
Results from a new clinical trial demonstrate that an eight-week mindfulness-based therapy — Mindfulness-Oriented Recovery Enhancement (MORE) — decreased opioid use and misuse while reducing chronic pain symptoms, with effects lasting as long as nine months. This is the first large-scale clinical trial to demonstrate that a psychological intervention can simultaneously reduce opioid misuse and […]
Children eat what they like, but food intake driven more by what they dislike
It is often said that “children eat what they like,” but the results of a new study by Penn State nutritionists and sensory scientists suggests that when it comes to meals, it is more accurate and more relevant to say, “children do not eat what they dislike.” There is an important difference, according to lead […]