This Video Game Is Helping Researchers Fight Dementia
This Video Game Is Helping Researchers Fight Dementia
Pattern of gene activity for ADHD
Researchers at the National Institutes of Health (NIH) have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study, led by scientists at the National Human Genome Research Institute (NHGRI), part of the NIH, found that individuals diagnosed with ADHD had differences in genes that code […]
A better model for type 2 diabetes: The Nile rat
Researchers have assembled the first reference genome for the Nile rat — a kind of genetic template of this species that may be used for laboratory and clinical studies. The hope, according to UC Santa Barbara researcher Huishi Toh, is that it will be useful for those who investigate Type 2 diabetes and neurological disorders […]
High-fat diet can provoke pain sensitivity without obesity, diabetes
A new study in mice from researchers at The University of Texas at Dallas suggests that a short-term exposure to a high-fat diet may be linked to pain sensations even in the absence of a prior injury or a preexisting condition like obesity or diabetes. The study, published Sept. 1 in the journal Scientific Reports, […]
Diet high in saturated fat can reprogram immune cells in mice
A new study by Portland State University researchers is the first to show that eating a diet exclusively high in saturated fats can reprogram the mouse immune system, making it better able to fight off infection but more susceptible to systemic inflammatory conditions, including sepsis. Brooke Napier, assistant professor of biology at PSU, led the […]
CDC: HIV Coinfection in Over 80% of Hospitalized Monkeypox Cases
In a cohort of patients hospitalized for monkeypox, four out of five had HIV and one in five died, CDC researchers said. Of the 57 adults hospitalized due to serious complications from monkeypox, 82.5% had HIV and 8.5% were receiving antiretroviral therapy, reported Maureen Miller, MD, of the CDC’s Monkeypox Emergency Response Team, and colleagues. […]
People With HIV More Likely to Be Hospitalized With Monkeypox?
Co-infection with HIV may increase the risk of hospitalization in patients with monkeypox, CDC researchers said, though other research did not confirm this. Among over 1,300 patients with monkeypox in eight U.S. jurisdictions, hospitalization was more common among those with HIV (8%) than those without the virus (3%), reported Kathryn G. Curran, PhD, of the […]
Inhibiting key metabolic enzyme shows promise against melanoma: The findings could yield new treatments for the most severe skin cancer
Researchers at Sanford Burnham Prebys, led by Ze’ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, these findings could lead to a new class of drugs to selectively treat melanoma, the most severe form of skin […]
Heterogeneous development of beta-cell populations in diabetes-resistant and -susceptible mice
Progressive dysfunction and failure of insulin-releasing β-cells is a hallmark of type 2 diabetes (T2D). DZD researchers have now shown that diabetes resistant and -susceptible mice respond differently to a carbohydrate-rich diet. The gene expression of the beta cells of the diabetes-resistant mice changed in such a way that a protective beta cell cluster developed. […]
Researchers Propose List of Core Symptoms to Better Define Long COVID
Researchers proposed a list of core symptoms that could offer a better working definition of long COVID, based on an observational cohort study from the Netherlands. Among over 1,700 COVID patients, 21.4% had at least one core symptom — including chest pain, breathing difficulties, painful muscles, ageusia or anosmia, tingling or heavy extremities, lump in […]