Comprehensive insulin signalling map shows interplay between genes and diet
Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a fundamental study of substantial importance. They say the authors share compelling evidence that sheds […]
Nutrients drive cellular reprogramming in the intestine
Researchers have unveiled an intriguing phenomenon of cellular reprogramming in mature adult organs, shedding light on a novel mechanism of adaptive growth. The study, which was conducted on fruit flies (Drosophila), provides further insights into dedifferentiation — where specialized cells that have specific functions transform into less specialized, undifferentiated cells like stem cells. Until now, […]
Global Incidence of Early-Onset Cancer Has Surged Since 1990
The global incidence of early-onset cancer has increased by 79% over the last three decades, researchers reported. In 2019, new cancer diagnoses in people under 50 totaled 3.26 million compared with 1.82 million in 1990, according to Xue Li, PhD, of Zhejiang University School of Medicine in China, and colleagues. Meanwhile, 1.06 million people under […]
Yeast studies show that diet in early life matters for lifelong health
Researchers at the Babraham Institute are proposing an alternative link between diet and ageing based on studies in yeast. Dr Jon Houseley and his team have published their experiments, showing that healthy ageing is achievable through dietary change without restriction by potentially optimising diet, and that ill-health is not an inevitable part of the ageing […]
Molecules in vegetables can help to ease lung infection
Researchers at the Francis Crick Institute have found that molecules in vegetables like broccoli or cauliflower help to maintain a healthy barrier in the lung and ease infection. The AHR — aryl hydrocarbon receptor — is a protein found at barrier sites like the gut and the lung. Natural molecules in cruciferous vegetables — for […]
Semaglutide medication may benefit 93 million U.S. adults
Researchers from the University of California, Irvine have just published a study that projects 93 million U.S. adults that are overweight and obese may be suitable for the 2.4 mg dosage of semaglutide, a weight loss medication known under the brand name Wegovy. They projected based on the known weight loss effects (15% average weight […]
Laboratory research finds gluten caused brain inflammation in mice
In what is believed to be a world first discovery, University of Otago researchers have found wheat gluten causes brain inflammation in mice. The research, led by Associate Professor Alex Tups, and published in the Journal of Neuroendocrinology, may be of importance for human physiology. “Mice are an excellent model to study human physiology. They […]
One third of normal-weight individuals are obese, according to study based on body fat percentage
Researchers from the School of Public Health at TAU’s Faculty of Medicine examined the anthropometric data of about 3,000 Israeli women and men and concluded that body fat percentage is a much more reliable indicator of an individual’s overall health and cardiometabolic risk than the BMI index, widely used in clinics today. The researchers suggest […]
Testing PD-1 Inhibition With Neoadjuvant Anti-HER2 Therapy in Breast Cancer
At the American Society of Clinical Oncology (ASCO) annual meeting, researchers reported on a multicenter, phase II trial exploring the efficacy and safety of adding pembrolizumab (Keytruda) to the standard-of-care treatment of paclitaxel (Taxol), trastuzumab (Herceptin), and pertuzumab (Perjeta; THP) in chemotherapy-naive patients with invasive, HER2-positive breast cancer. In this exclusive MedPage Today video, Jin […]
Colorful fresh foods improve athletes’ vision: Visual range is a critical asset for top athletes in almost any sport
Nutrition is an important part of any top athlete’s training program. And now, a new study by researchers from the University of Georgia proposes that supplementing the diet of athletes with colorful fruits and vegetables could improve their visual range. The paper, which was published in Exercise and Sport Sciences Reviews, examines how a group […]