How to rejuvenate the immune system of elderly people and reduce their risk of infectious disease: Study results identify reason for why older adults are significantly more susceptible to infectious diseases
A new study, led by researchers from the University of California, Irvine, identifies a reason for why older adults are significantly more susceptible to infectious diseases than younger people, a critical societal issue most recently exemplified by the COVID-19 pandemic. Study results also pave the way for new potential therapeutic targets to rejuvenate the immune […]
Not all dietary fiber is created equal: cereal fiber but not fruit or vegetable fibers are linked with lower inflammation: Cereal fiber is associated with a lower risk of cardiovascular disease
Researchers at Columbia University Mailman School of Public Health and colleagues evaluated whether dietary fiber intake was associated with a decrease in inflammation in older adults and if fiber was inversely related to cardiovascular disease. The results showed that total fiber, and more specifically cereal fiber but not fruit or vegetable fiber, was consistently associated […]
Not all dietary fiber is created equal: cereal fiber but not fruit or vegetable fibers are linked with lower inflammation: Cereal fiber is associated with a lower risk of cardiovascular disease
Researchers at Columbia University Mailman School of Public Health and colleagues evaluated whether dietary fiber intake was associated with a decrease in inflammation in older adults and if fiber was inversely related to cardiovascular disease. The results showed that total fiber, and more specifically cereal fiber but not fruit or vegetable fiber, was consistently associated […]
Genetic ‘hotspots’ that speed up and slow down brain aging could provide new targets for Alzheimer’s drugs
Researchers from a USC-led consortium have discovered 15 “hotspots” in the genome that either speed up brain aging or slow it down — a finding that could provide new drug targets to resist Alzheimer’s disease and other degenerative brain disorders, as well as developmental delays. The research appears online today in Nature Neuroscience. “The big […]
Carbs, sugary foods may influence poor oral health
The foods we eat on a regular basis influence the makeup of the bacteria — both good and bad — in our mouths. And researchers are finding that this collective of bacteria known as the oral microbiome likely plays a large role in our overall health, in addition to its previously known associations with tooth […]
New method for probing the bewildering diversity of the microbiome
In recent years, researchers have begun to explore the vast assemblage of microbes on and within the human body. These include protists, archaea, fungi, viruses and vast numbers of bacteria living in symbiotic ecosystems. Known collectively as the human microbiome, these tiny entities influence an astonishing range of activities, from metabolism to behavior and play […]
Don’t Wait, Ablate to Prevent VT Episodes After an ICD Shock?
WASHINGTON — Researchers made a strong case that earlier was better when it comes to catheter ablation of ventricular tachycardias (VTs) in people with implantable cardiac defibrillators (ICDs). After a first ICD shock, 23 patients with ischemic or non-ischemic cardiomyopathy soon underwent radiofrequency VT ablation and ended up with 4% incidence of worsening heart failure […]
Study shows how bioactive substance inhibits important receptor: Results raise hope for new drugs against cancer and brain diseases
The A2A receptor regulates how vigorously the innate immune system attacks diseased cells. Researchers at the University of Bonn have now been able to show for the first time how an important inhibitor binds to the receptor. In the future, the results will facilitate the targeted search for molecules that give the innate immune system […]
Stem cell secrets allow researchers to revamp reprogramming: Researchers have identified factors required to generate naïve stem cells by reprogramming
Researchers from the Babraham Institute’s Epigenetics research programme have been able to learn more about naïve stem cell reprogramming following a genome wide functional screen. Their research, published today in Science Advances, describes the critical regulators of reprogramming and offers opportunities for a more efficient, faster way to generate human naïve pluripotent stem cells. Human […]
Researchers discover intake of FDA-approved drug modulates disease progression in Alzheimer’s disease model
Indiana University School of Medicine researchers found that niacin limits Alzheimer’s disease progression when used in models in the lab, a discovery that could potentially pave the way toward therapeutic approaches to the disease. The study, recently published in Science Translational Medicine, investigates how niacin modulates microglia response to amyloid plaques in an Alzheimer’s disease […]