Oral Drug Gains Steam as On-Demand Option for Hereditary Angioedema Attacks
WASHINGTON — The investigational oral drug sebetralstat provided on-demand relief during tissue swelling attacks from hereditary angioedema (HAE), a phase III study showed. Following self-administration, time to the beginning of symptom relief was reduced from a median 6.7 hours with placebo to 1.6 hours with a 300-mg dose of the plasma kallikrein inhibitor (P<0.0001) and […]
Morphine Quieted Cough in Patients With Idiopathic Pulmonary Fibrosis
A brief course of morphine provided some relief for patients with cough related to idiopathic pulmonary fibrosis (IPF) in a small, phase II double-blind crossover trial. Two weeks of low-dose controlled-release morphine reduced objective awake cough frequency by 39.4% over a placebo treatment phase (95% CI -54.4 to -9.4), reported Philip Molyneaux, PhD, of Imperial […]
Menopausal Women With Obesity Endure Worse Symptoms, Less HT Relief
PHILADELPHIA — Women with obesity may experience worse menopausal symptoms and see less relief from hormone therapy (HT), according to a pilot study. When compared with women without obesity, those with a BMI of 30 or greater were significantly more likely to report menopause-related vasomotor symptoms like hot flashes and night sweats (74% vs 45%, […]
Ease Your TMJ Pain With These Expert Recommend Products
For those with frequent or chronic TMJ pain, it can be difficult to find relief from this particularly relentless facial discomfort. It’s a painful and misunderstood condition that affects 5% (and possibly up to 12%) of individuals, including young people, which makes it a rarity in the world of chronic pain. The lack of resources, […]
Opinion | ‘I’ve Never Seen Anything Like This’ in the Pediatric ED
Walking out of a shift in the pediatric emergency department (ED) lately is a heavy mix of relief, guilt, and pure exhaustion. Wading through wall-to-wall families, huddled in blankets and sweatshirts through long hours waiting to be seen, you wish you could do more, find more beds, create more staff. You’ve spent hours running from […]
Ivermectin: Still on a Losing Streak as COVID-19 Treatment
WASHINGTON — There were no differences in relief from mild-to-moderate COVID-19 symptoms for patients on ivermectin versus placebo, according to the ongoing ACTIV-6 trial. Among >1,000 vaccinated and unvaccinated patients, the median time to recovery was 12 days for those in the ivermectin group and 13 days in the placebo group, reported Matthew McCarthy, MD, […]
Recent Developments in Allergic Asthma
Forty-two weeks into 2022, the year has seen significant progress in bringing relief to patients with allergic asthma. Among them: research identifying novel types of precipitating factors (literally, in one recent study), better understanding of air pollution’s contributions to asthma exacerbations, and insights into how climate change may affect asthma patients. And drug developers in […]
Benzodiazepines or Antihistamines for Acute Vertigo?
Moderately strong evidence suggested antihistamines provide greater acute vertigo relief than benzodiazepines, a meta-analysis showed. Single-dose antihistamines led to a 16.1-point (95% CI 7.2-25.0) greater decrease in vertigo symptom scores on a 100-point visual analog scale (VAS) compared with single-dose benzodiazepines at about 2 hours after treatment, reported Benton Hunter, MD, of Indiana University School […]
Therapeutic Use of Cannabis: Risks, Benefits, Legality
ORLANDO — As more patients seek cannabis products for pain relief and other indications, clinicians’ knowledge of the products, risks, and benefits becomes paramount in guiding safe and effective use, a primary care practitioner in pain management said here. As many as 80% of patients who seek medical cannabis want it for pain, and about […]
Innovation, Construction and Provider Relief Grants Available – Wyoming Department of Health
Innovation, Construction and Provider Relief Grants Available June 6, 2022 Health and human service providers across the state are invited to consider applying for innovation, construction and provider relief grants offered through the Wyoming Department of Health (WDH). Earlier this year, the Wyoming Legislature appropriated $5 million in federal American Rescue Plan Act (ARPA) direct […]