FDA Panel Votes Against Broad Talazoparib-Enzalutamide Label in Prostate Cancer
An FDA advisory committee on Wednesday unanimously voted against recommending approval of the PARP inhibitor talazoparib (Talzenna) plus enzalutamide (Xtandi) for all patients with metastatic castration-resistant prostate cancer (mCRPC). In an 8-0 vote, members of the Oncologic Drugs Advisory Committee (ODAC) said the available data from the TALAPRO-2 trial do not support a favorable risk-benefit […]
CDC Advisors Support Updated COVID Shots for All
The CDC’s Advisory Committee on Immunization Practices (ACIP) voted 13 to 1 in favor of recommending updated, monovalent, XBB-targeting COVID-19 shots for everyone age 6 months and up. Specifically, the language in the recommendation supports the “2023-2024” vaccines as authorized or approved by the FDA — in order to cover the recently green-lighted mRNA shots, […]
Medicine Doesn’t Stop at the Bedside
In June 2021, the American Academy of Neurology (AAN) issued a statement recommending the prohibition of neck restraints in law enforcement. Around the same time, the American Medical Association (AMA) issued a statement denouncing the pseudoscientific and racist concept of “excited delirium” and categorized racism as a threat to public health. In 2018, the American […]