High-Dose Leptin Reversed Severe Genetic Obesity in Two Patients
Personalized recombinant leptin treatment helped reverse severe, early-onset obesity in two children carrying rare antagonistic leptin genetic variants, a study showed. In the double case report, two unrelated children — a 14-year-old boy and a 2-year-old girl — presented with what appeared to be leptin dysfunction, marked by intense hyperphagia, lack of satiety, and severe […]
Shingrix OK’d For Immunocompromised Adults
FDA expanded the approval of Shingrix, an adjuvanted recombinant zoster vaccine, for adults at increased risk of shingles due to immunosuppression, manufacturer GlaxoSmithKline (GSK) announced on Monday. The expanded indication is for adults ages 18 and older at a greater risk of shingles due to “immunodeficiency or immunosuppression caused by known disease or therapy.” The […]
Can You Get Shingles If You Have Had Chickenpox?
Medically Reviewed on 6/30/2021 References Medscape. Zoster Vaccine Recombinant (Rx). https://reference.medscape.com/drug/shingrix-zoster-vaccine-recombinant-1000163 Centers for Disease Control and Prevention. Shingles Vaccination. https://www.cdc.gov/vaccines/vpd/shingles/public/shingrix/index.html U.S. Department of Health and Human Services (HHS). Vaccines by Disease. https://www.vaccines.gov/diseases/shingles WebMD. Understanding Shingles — the Basics. https://www.webmd.com/skin-problems-and-treatments/guide/understanding-shingles-basics WebMD. Shingles. https://www.webmd.com/skin-problems-and-treatments/shingles/shingles-skin#1 Centers for Disease Control and Prevention. Shingles (Herpes Zoster). https://www.cdc.gov/shingles/index.html Janniger CK. Herpes […]