Meta-Analysis Reaffirms Role of ADT With Radiotherapy in Prostate Cancer
CHICAGO — The use of androgen deprivation therapy (ADT) in conjunction with radiotherapy, as well as its prolonged use in the adjuvant setting, improved metastasis-free survival (MFS) and overall survival (OS) in patients with localized prostate cancer, a meta-analysis found. Adding ADT to radiotherapy significantly improved 12-year rates of MFS, the primary endpoint (HR 0.83, […]
Risk of Premature Death Seen in Testicular Cancer Survivors
Treating testicular cancer (TC) with platinum-based chemotherapy (PBCT) and radiotherapy (RT) was associated with an increased risk of long-term non-TC mortality, a Norwegian population-based cohort study found. Over a median follow-up of 18.7 years, overall excess non-TC mortality was 23% in men diagnosed with TC compared with the general population (standardized mortality ratio [SMR] 1.23, […]
Single- or Multi-Fraction SABR for Lung Oligometastases?
Both single-fraction and multifraction stereotactic ablative body radiotherapy (SABR) had acceptable safety and comparable efficacy for patients with pulmonary oligometastases, according to results from a phase II randomized trial. The primary endpoint of grade 3 or higher adverse events (AEs) related to treatment within 1 year of SABR was similar between the single-fraction arm (5%) […]