AI for Radiation Therapy Works, but Is it Fully Trusted?
The use of artificial intelligence in creating radiation treatment plans for prostate cancer appeared to be a success, according to a blinded, head-to-head study. Overall, radiation oncologists considered the vast majority — 89 of 100 — of machine learning (ML)-generated plans clinically acceptable for treatment, reported Thomas Purdie, PhD, and colleagues at Princess Margaret Cancer […]
Arginine, an inexpensive oral drug, could enhance radiation therapy for cancer
Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute. The study, published Nov. 5 in Science Advances, reported the results of administering arginine, […]
Benefits of Adjuvant Radiation in DCIS Persist Out to 15 Years
Adjuvant radiation therapy (RT) for good-risk ductal carcinoma in situ (DCIS) reduced long-term ipsilateral breast recurrence (IBR) by more than 50% compared with observation, results of a large intergroup study showed. RT, following surgery with or without tamoxifen, decreased 15-year IBR from 15.1% with observation to 7.1%. RT also reduced the odds of invasive local […]
Study Confirms, Clarifies Excess Mortality in Testicular Cancer Survivors
Platinum-based chemotherapy (PBCT) and radiation therapy (RT) for testicular cancer significantly increased the risk of premature death from other causes, especially secondary cancers, a large Norwegian study showed. Overall, the 5,700 men included in the analysis had a 23% excess mortality from causes other than testicular cancer after treatment with PBCT or RT, as compared […]
Could Docetaxel Have Role in Unfavorable-Risk Prostate Cancer?
Adding docetaxel to androgen deprivation therapy (ADT) plus radiation therapy (RT) failed to improve survival in unfavorable-risk prostate cancer, though the combination may hold benefit for certain patients, long-term results of a randomized trial found. While the regimen did not prolong overall survival (OS) among all men with unfavorable-risk nonmetastatic cancer after a median of […]
Reducing the melting of Greenland ice cap using solar geoengineering?
Injecting sulphur into the stratosphere to reduce solar radiation and stop the Greenland ice cap from melting. An interesting scenario, but not without risks. Climatologists from the University of Liège have looked into the matter and have tested one of the scenarios put forward using the MAR climate model developed at the University of Liège. […]