Upfront Transplant Prevails Again in Newly Diagnosed Myeloma
An immunomodulatory-free carfilzomib (Kyprolis)-based triplet regimen failed to prove non-inferior to autologous hematopoietic stem-cell transplantation (HSCT) for the upfront treatment of newly diagnosed multiple myeloma, a randomized trial from the U.K. found. The open-label phase II CARDAMON study included nearly 300 patients, with 57.7% achieving at least a very good partial response (VGPR) with the […]
Imagining future guilt helps athletes turn away from doping
Appealing to athletes’ sense of ‘future guilt’ through psychological intervention could prove a powerful weapon in the fight against doping, according to a new study. Researchers discovered that making elite athletes picture how guilty they might feel about using banned performance enhancing drugs produced a more powerful initial reaction than initiatives educating sportspeople about the […]