Small protein protects pancreatic cells in model of type 1 diabetes
A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease. The small protein that first made headlines as an “exercise mimetic” increasingly appears to also have a big role in regulating the […]
Researchers find immune component to rare neurodegenerative disease: Niemann-Pick disease type C, long thought to be tied to cholesterol metabolism, may eventually be treated with immune inhibitors
UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C. The finding, made in mouse models and published online in Nature, could offer a powerful new therapeutic target for Niemann-Pick disease type C, a condition that was identified more than a century ago but still […]