High PSMA Predictive of Good Response to Radioisotope Therapy in Prostate Cancer
Uptake of a transmembrane protein, which is expressed by virtually all prostate cancers, on imaging could be a viable predictive biomarker of patient response to isotope-based therapy, according to data from the phase II TheraP trial. High baseline prostate-specific membrane antigen (PSMA) uptake on PET was predictive of a favorable response to treatment with lutetium-177 […]
Higher CRP Levels Tied to Cognitive Problems in Older Breast Cancer Survivors
Higher levels of C-reactive protein (CRP) were associated with cognitive problems in older breast cancer survivors, a longitudinal analysis showed. Among participants of the Thinking and Living With Cancer study, breast cancer survivors with higher CRP levels than others reported statistically worse cognition (P=0.040) — a relationship that was not seen in women with no […]
Is it really healthy to restrict protein intake for kidney transplant recipients? Study suggests that sufficient protein intake is necessary to prevent sarcopenia after kidney transplantation
Conventional wisdom holds that low protein intake is essential for kidney disease patients. However, scientists from Osaka Metropolitan University demonstrated that it might not always be the case with their recent study on the relationship between protein intake and skeletal muscle mass in kidney transplant recipients. Their findings were published in Clinical Nutrition. Chronic kidney […]
Taste sensors keep proteins in order in flies: New role for adult proteins in development
A set of genes that promote sweet taste sensation is also crucial for protein management during fly development, according to a new study by Eugenia Piddini of the University of Bristol, United Kingdom, and colleagues, publishing July 21stin the open-access journal PLOS Biology. The finding expands the understanding of a key process in successful development, […]
Balancing protein in your diet could improve water quality: Eating too much protein adds to nitrogen pollution in US waters
Balancing how much protein you eat with the amount your body needs could reduce nitrogen releases to aquatic systems in the U.S. by 12% and overall nitrogen losses to air and water by 4%, according to a study from the University of California, Davis. Protein consumption in the United States, from both plant and animal […]
Higher protein intake while dieting leads to healthier eating
Eating a larger proportion of protein while dieting leads to better food choices and helps avoid the loss of lean body mass, according to a Rutgers study. An analysis of pooled data from multiple weight-loss trials conducted at Rutgers shows that increasing the amount of protein even slightly, from 18 percent of a person’s food […]
Stress protein in fibroblasts may be a good target for future cancer drugs: ATF4 protein works in tumors and tumor-supporting fibroblasts to promote tumor survival
A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future cancer treatments, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania. The researchers, whose findings appear in Nature […]
Protein supplement helps control Type 2 diabetes
Drinking a small amount of whey protein before meals has been shown to help people with type 2 diabetes control their blood sugars. In a study, which holds potential for dietary management of the condition, people with type 2 diabetes drank a pre-made shot before meals which contained a low dose of whey protein. They […]
New COVID Vaccines From Canada, China Score in International Trials
A plant-based vaccine developed in Canada and a protein subunit vaccine from China proved safe and effective against symptomatic COVID-19, a pair of phase III trials found. The two-dose plant-based vaccine, a combination of coronavirus-like particles in plants plus an adjuvant, showed 69.5% efficacy (95% CI 56.7-78.8) against any symptomatic disease caused by five pre-Omicron […]
Did Black Patients with COVID-19 See Greater Benefits With Novel Mab Therapy?
Hospitalized Black/African-American patients with COVID-19, and a baseline C-reactive protein (CRP) <150 mg/L, experienced a “markedly greater improvement” in survival without ventilation (SWOV), according to an analysis of LIVE-AIR study data. While SWOV at 28 days was improved among all patients with the agent versus placebo (hazard ratio 2.54, 95% CI 1.46-4.41, P=0.0009), the benefit […]