Dementia Predicted 10 Years Before Diagnosis
Blood protein profiles predicted future dementia in healthy adults, a large longitudinal study showed. Blood samples from over 50,000 people in the U.K. Biobank showed that four proteins — glial fibrillary acidic protein (GFAP), neurofilament light (NfL), growth differentiation factor-15 (GDF-15), and latent-transforming growth factor beta-binding protein 2 (LTBP2) — consistently were associated with subsequent […]
Year in Review: Follicular Lymphoma
Studies demonstrating high response rates and manageable safety profiles, along with FDA approvals, have supported bispecific antibodies as promising treatment options for follicular lymphoma. At the start of 2023, a new option became available with the accelerated approval of mosunetuzumab (Lunsumio) late last year. The first-in-class bispecific monoclonal antibody works by inducing CD20-directed CD3 T-cell […]
Post-COVID Cognitive Deficits Linked With Clotting Proteins
Two distinct blood biomarker profiles predicted cognitive deficits 6 and 12 months after COVID-19, prospective U.K. data showed. Both biomarker profiles featured proteins involved in coagulation, reported Maxime Taquet, PhD, of the University of Oxford in England, and co-authors in Nature Medicine. Among 1,800 patients hospitalized for COVID-19 during the first wave of the pandemic, […]