ADHD stimulants may increase risk of heart damage in young adults, study finds
Young adults who were prescribed stimulant medications for attention-deficit/hyperactivity disorder (ADHD) were significantly more likely to develop cardiomyopathy (weakened heart muscle) compared with those who were not prescribed stimulants, in a study presented at the American College of Cardiology’s Annual Scientific Session. The study found that people prescribed stimulants such as Adderall and Ritalin were […]
Benzodiazepines Tied to Worse Outcomes in Progressive Supranuclear Palsy
People with progressive supranuclear palsy (PSP) who were prescribed benzodiazepine derivatives had a faster decline in PSP Rating Scale (PSPRS) scores than those who didn’t have benzodiazepines, a post hoc analysis showed. In a secondary analysis of concomitant drugs used in a phase II/III clinical trial, only one medication class — benzodiazepine derivatives, including lorazepam, […]
Researchers show effectiveness of migraine drug in weight loss: Over the course of a month, mice taking triptan migraine drugs ate less and lost more weight than other animals
Triptans, a commonly prescribed class of migraine drugs, may also be useful in treating obesity, a new study by scientists at UT Southwestern suggests. In studies on obese mice, a daily dose of a triptan led animals to eat less food and lose weight over the course of a month, the team reported in the […]
Researchers show effectiveness of migraine drug in weight loss: Over the course of a month, mice taking triptan migraine drugs ate less and lost more weight than other animals
Triptans, a commonly prescribed class of migraine drugs, may also be useful in treating obesity, a new study by scientists at UT Southwestern suggests. In studies on obese mice, a daily dose of a triptan led animals to eat less food and lose weight over the course of a month, the team reported in the […]
ADHD Drugs May Treat Alzheimer’s Cognitive Symptoms Effectively
Drugs with principally noradrenergic action — including ones prescribed for attention deficit-hyperactivity disorder (ADHD) or to treat hypertension or depression — may effectively treat cognitive symptoms and apathy in Alzheimer’s disease, a systematic review and meta-analysis suggested. Noradrenergic drugs showed a significant small positive effect on global cognition with a standardized mean difference (SMD) of […]
Nanotherapy offers new hope for the treatment of Type 1 diabetes
Individuals living with Type 1 diabetes must carefully follow prescribed insulin regimens every day, receiving injections of the hormone via syringe, insulin pump or some other device. And without viable long-term treatments, this course of treatment is a lifelong sentence. Pancreatic islets control insulin production when blood sugar levels change, and in Type 1 diabetes, […]
‘Concerning’ Opioid Prescribing in Patients With Cirrhosis
Nearly one in five patients with cirrhosis were prescribed opioids during outpatient visits, more often than not by a primary care physician (PCP), according to a national analysis of over 10 million ambulatory visits. From 2006 to 2016, 17% of all outpatient visits for patients with cirrhosis resulted in an opioid prescription, usually a refill, […]
Potential COVID-19 medication found among tapeworm drugs: Re-engineered compound fights both cytokine storm and viral replication, experiments show
A group of medications long prescribed to treat tapeworm has inspired a compound that shows two-pronged effectiveness against COVID-19 in laboratory studies, according to a new publication appearing online in the journal ACS Infectious Disease. The compound, part of a class of molecules called salicylanilides, was designed in the laboratory of Professor Kim Janda, PhD, […]
Common weight-loss drug successfully targets fat that can endanger heart health
Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide. In adults who are overweight or have obesity combined with high cardiovascular risk, once-daily liraglutide combined with lifestyle interventions significantly lowered two types of fat that have been associated with risk to heart health: visceral fat […]