Genetic Risk Score Predicts Hypertensive Disorders of Pregnancy
With new genetic variants identified for preeclampsia and gestational hypertension, researchers created polygenic risk scores (PRS) that may better identify candidates for prophylactic low-dose aspirin among pregnant mothers. There were 18 independent genetic loci significantly associated with hypertensive disorders of pregnancy (HDPs) — 12 of them new (i.e., MTHFR-CLCN6, WNT3A, NPR3, PGR, and RGL3) — […]