Dual Therapy Holds Its Own in Treatment-Naive HIV
MONTREAL — A two-drug combination using a generic formulation of the protease inhibitor darunavir/ritonavir plus lamivudine appeared to control HIV as well as the same combination with added tenofovir, according to results of the phase IV ANDES trial reported here. In the intention-to-treat analysis, 91% patients on the dual therapy achieved undetectable viral loads using […]
CDC: Monkeypox May Present With Genital Sores, No Prior Fever
Clinicians should be highly suspicious for monkeypox infection if a patient has an unusual rash, plus a travel history to a country with confirmed cases, among other factors, the CDC said on Friday. In a Health Alert Network advisory, the agency provided more detail about the type of lesions characteristic of monkeypox, as well as […]
More Evidence Hybrid Immunity Confers Highest Level of COVID Protection
Hybrid immunity from a COVID-19 infection plus a vaccine provided an immune boost against symptomatic disease, as well as severe outcomes, Brazilian researchers found. Among people who survived a COVID infection from Feb. 24, 2020 to Nov. 11, 2021, vaccine effectiveness against symptomatic disease at least 14 days after series completion was 44.0% (95% CI […]
Could Docetaxel Have Role in Unfavorable-Risk Prostate Cancer?
Adding docetaxel to androgen deprivation therapy (ADT) plus radiation therapy (RT) failed to improve survival in unfavorable-risk prostate cancer, though the combination may hold benefit for certain patients, long-term results of a randomized trial found. While the regimen did not prolong overall survival (OS) among all men with unfavorable-risk nonmetastatic cancer after a median of […]