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COX-2 Inhibitor Added to Levonorgestrel Improved Emergency Contraception Efficacy

Taking the oral cyclo-oxygenase (COX)-2 inhibitor piroxicam in combination with levonorgestrel improved emergency contraception efficacy versus levonorgestrel alone, with no additional adverse events, a randomized controlled trial showed. Piroxicam 40 mg combined with levonorgestrel 1.5 mg prevented 94.7% of expected pregnancies compared with 63.4% with levonorgestrel plus placebo (P<0.0001), reported Raymond Hang Wun Li, MD, […]

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