Craving snacks after a meal? It might be food-seeking neurons, not an overactive appetite
People who find themselves rummaging around in the refrigerator for a snack not long after they’ve eaten a filling meal might have overactive food-seeking neurons, not an overactive appetite. UCLA psychologists have discovered a circuit in the brain of mice that makes them crave food and seek it out, even when they are not hungry. […]
5 Signs You Should Get A Colonoscopy Before You Turn 45
SDI Productions via Getty Images The recommended age to begin colonoscopy screening is 45, but some people should start sooner. It’s been frequently reported that colorectal cancer rates are increasing in young people in the United States. In fact, according to the American Cancer Society, cases of colorectal cancer in people 55 and under have […]
How Often Should Immunocompromised People Get a COVID Booster?
Preventing SARS-CoV-2 infection in immunocompromised people hasn’t gotten any easier as the pandemic trundles on into its fifth year. The monoclonal antibody tixagevimab-cilgavimab (Evusheld) has long gone by the wayside for pre-exposure prophylaxis and no replacements are on the horizon. Other prevention strategies among the general population, such as mask-wearing, have all but disappeared. Vaccination […]
Common antibiotic found useful in accelerating recovery in tuberculosis patients
Globally, an estimated 10 million people develop tuberculosis (TB) each year and the disease remains a leading cause of death from a single infectious agent. Standard short-course anti-TB treatment still requires a regimen of at least six months of antimicrobial drugs, and drug-resistant TB is an increasing public health threat. Even after the traces of […]
Most People With TB Report No Persistent Cough
A significant proportion of people in the community with pulmonary tuberculosis (TB) have subclinical disease, according to a meta-analysis involving survey studies across Africa and Asia. In adjusted analyses, 82.8% (95% CI 78.6-86.6) of participants with TB reported no persistent cough and 62.5% (95% CI 56.6-68.7) reported no cough at all, according to Frank Cobelens, […]
Semaglutide Cuts Liver Disease Severity in People With HIV
DENVER — Semaglutide (Ozempic) reduced the amount of liver fat by nearly a third in people with HIV and metabolic dysfunction-associated steatotic liver disease (MASLD), the open-label phase IIb SLIM LIVER study showed. In the single-arm trial, the absolute change in intrahepatic triglyceride (IHTG) content across all participants was -4.2% (95% CI -5.4 to -3.1, […]
Interventions Can Reduce CVD Risk Factors in HIV Patients, Studies Show
DENVER — Efforts aimed at lowering blood pressure (BP) and cholesterol in people with HIV can succeed, two randomized trials presented here demonstrated. In the first, prehypertensive Haitians on stable antiretroviral therapy (ART) who received early treatment with a calcium channel blocker experienced significantly greater reductions in systolic and diastolic BP compared with those who […]
Semaglutide Reduced Inflammatory Biomarkers in HIV Patients With Lipohypertrophy
DENVER — People with HIV who received semaglutide (Ozempic, Wegovy) had reduced levels of several inflammatory biomarkers associated with cardiovascular disease, a randomized controlled trial showed. After 32 weeks, interleukin (IL)-6 levels decreased by 18.8%, high-sensitivity C-reactive protein (hsCRP) levels decreased by 39.9%, and soluble CD163 levels decreased by 12.3% with the GLP-1 receptor agonist, […]
Investigational Agent Shows Benefit in Myasthenia Gravis
The investigational monoclonal antibody batoclimab led to significant improvement in activities of daily living in people with generalized myasthenia gravis (gMG), a multicenter phase III trial found. The rate of sustained improvement on Myasthenia Gravis Activities of Daily Living (MG-ADL) scores for antibody-positive patients in the first treatment cycle was 58.2% in the batoclimab group […]
We’re Dentists. Here Are 5 Issues We’d Never, Ever Ignore.
LOADINGERROR LOADING When it comes to the basics of dental hygiene, most people know to follow the key rules ― like brushing twice a day ― but many quickly discount the seemingly-small dental problems that occur. And that can be dangerous. “What a lot of patients don’t understand is your dental health is pertinent to […]