Not So Fast for NSAID Closure of Heart Defect in Preterm Newborns
Early ibuprofen administration did not help babies born preterm with patent ductus arteriosus (PDA), as waiting for the heart defect to close on its own was associated with non-inferior, perhaps even better clinical outcomes, in a randomized trial. For infants born with moderate or larger PDAs, expectant management worked at least as well as early […]