Semaglutide Cuts Liver Disease Severity in People With HIV
DENVER — Semaglutide (Ozempic) reduced the amount of liver fat by nearly a third in people with HIV and metabolic dysfunction-associated steatotic liver disease (MASLD), the open-label phase IIb SLIM LIVER study showed. In the single-arm trial, the absolute change in intrahepatic triglyceride (IHTG) content across all participants was -4.2% (95% CI -5.4 to -3.1, […]
Semaglutide Reduced Inflammatory Biomarkers in HIV Patients With Lipohypertrophy
DENVER — People with HIV who received semaglutide (Ozempic, Wegovy) had reduced levels of several inflammatory biomarkers associated with cardiovascular disease, a randomized controlled trial showed. After 32 weeks, interleukin (IL)-6 levels decreased by 18.8%, high-sensitivity C-reactive protein (hsCRP) levels decreased by 39.9%, and soluble CD163 levels decreased by 12.3% with the GLP-1 receptor agonist, […]
No Increased Risk of Suicidal Ideation With GLP-1 Drugs
Despite recent concerns to the contrary, semaglutide (Wegovy, Ozempic) carried a lower risk of suicidal ideation in patients with obesity or type 2 diabetes, according to retrospective analyses of the two patient populations. An analysis of 240,618 patients who were overweight or obese showed that those taking semaglutide — a glucagon-like peptide 1 (GLP-1) receptor […]
My Incurable Condition Is A Potential Ozempic Side Effect. Trust Me — Weight Loss Isn’t Worth This.
Boxes of the diabetes drug Ozempic rest on a pharmacy counter on April 17 in Los Angeles. Mario Tama via Getty Images In case you’ve been living under a rock and missed the hype, Ozempic is an injectable diabetes drug that’s become popular as an off-label medication for weight loss. It mimics GLP-1, a naturally […]
Could Semaglutide Help Curb Addictive Behaviors?
Semaglutide (Ozempic, Wegovy) and other drugs in its class are widely known for their role in managing type 2 diabetes and suppressing appetite. They may also prove helpful one day in curbing certain addictive behaviors like alcohol use and smoking. Preclinical research has shown promising results, and endocrinologists and patients have described, anecdotally, reduced cravings […]
The feeling of hunger itself may slow aging in flies
From low-carb to intermittent fasting, surgery to Ozempic — people turn to a seemingly never-ending array of diets, procedures and drugs to lose weight. While it has been long understood that limiting the amount of food eaten can promote healthy aging in a wide range of animals, including humans, a new study from University of […]