Surveillance Still Not an Option for Many With Subsegmental Pulmonary Embolism
Only a narrow pool of outpatients with acute subsegmental pulmonary embolism (PE) may be candidates for structured surveillance without anticoagulation based on current guideline restrictions, a retrospective study found. At one large integrated health system, only one person out of 229 low-risk adults received structured surveillance for subsegmental PE — a “remarkably low” 0.4% over […]
FDA Approves First Oral Antiviral Drug for COVID-19
The FDA has granted full approval to nirmatrelvir-ritonavir (Paxlovid) for treating adult outpatients with mild to moderate COVID-19 who are at risk for severe disease, the agency announced on Thursday. “Today’s approval demonstrates that Paxlovid has met the agency’s rigorous standards for safety and effectiveness, and that it remains an important treatment option for people […]
Ketamine Matches ‘Gold Standard’ in Major Depression Trial
SAN FRANCISCO — When it came to improving treatment-resistant major depression in outpatients without psychotic features, ketamine worked just as well as electroconvulsive therapy (ECT), the ELEKT-D randomized trial found. Following a 3-week treatment period, 55.4% of the patients in the ketamine group and 41.2% of those in the ECT group had a treatment response, […]
Remdesivir Appears Effective in COVID Outpatients, Too
Remdesivir (Veklury) reduced risk of hospitalizations by 87% compared with placebo in outpatients at high risk of progression to severe COVID-19, a researcher said. While the raw numbers were small — two in the remdesivir arm versus 15 in the placebo arm — the remdesivir arm had a significantly lower risk of hospitalization (0.7% vs […]