SABR Offers New Hope for Older Patients With Inoperable Kidney Cancer
SAN DIEGO — Stereotactic ablative body radiotherapy (SABR) was an effective, noninvasive strategy for treating primary renal cell carcinoma (RCC) in patients who were not suitable for surgery, according to the FASTRACK II trial. In the prospective, phase II study of 70 patients, none had local progression of kidney cancer during the trial lifetime (median […]
Breathing Support Type Matters for Preventing Extubation Failure in the PICU
Postextubation use of certain modes of noninvasive respiratory support was associated with fewer incidents of extubation failure in critically ill children, a meta-analysis found. Compared with conventional oxygen therapy, both continuous positive airway pressure (CPAP; OR 0.43, 95% credible interval [CrI] 0.17-1.0) and high-flow nasal cannula (HFNC; OR 0.64, 95% CrI 0.24-1.0) appeared more effective […]
Helmet CPAP Leads Noninvasive Ventilation Therapies for Acute Respiratory Failure
The available noninvasive oxygenation strategies varied in their effectiveness in treating acute hypoxemic respiratory failure (AHRF), according to a meta-analysis of randomized trials. Helmet continuous positive airway pressure (CPAP) was the only modality that had at least moderate certainty evidence backing a probable mortality reduction compared with standard oxygen therapy (SOT; 231 fewer deaths per […]
Blood-Based Biomarkers Prove Mettle in Liver Disease Diagnosis
Multiple noninvasive blood biomarkers for metabolic liver disease met accuracy assessments for diagnosing metabolic liver disease in the first step of an advanced qualification system to better utilize these noninvasive tools, a researcher said. Top-line analyses of the Non-Invasive Biomarkers of Metabolic Liver Disease (NIMBLE) Stage 1 initiative found high sensitivity and specificity for the […]
Pioneering noninvasive technique for neurological conditions
Indiana University School of Medicine researchers are developing a new, noninvasive brain stimulation technique to treat neurological disorders, including pain, traumatic brain injury (TBI), epilepsy, Parkinson’s disease, Alzheimer’s disease and more. “Given the increasing use of brain stimulation in human brain study and treatment of neurological diseases, this research can make a big impact on […]