Elotuzumab Misses Mark Again as Frontline Treatment for Multiple Myeloma
Elotuzumab (Empliciti) failed for a third time to improve progression-free survival (PFS) in newly diagnosed multiple myeloma when added to standard therapy, a large randomized trial showed. After 4 years of follow-up, neither the median PFS nor the 3-year PFS differed significantly among four treatment groups who received lenalidomide (Revlimid) and bortezomib (Velcade) plus dexamethasone […]
Clinical Challenges: Test Your Knowledge on New Breast Cancer Treatments
The number of available treatment options for patients newly diagnosed with breast cancer continues to grow. The following three-question quiz will test one aspect from each article in our “Clinical Challenges” series on advanced breast cancer, which covered managing adverse effects of novel therapies and sequencing of treatments in metastatic HER2-positive breast cancer and metastatic […]
FLT3 Inhibitor Doubles Overall Survival in Acute Myeloid Leukemia
Incorporating quizartinib into standard treatment for newly diagnosed acute myeloid leukemia (AML) followed by maintenance therapy with the investigational FLT3 inhibitor improved survival for patients with internal-tandem-duplication (ITD) mutations of FLT3, a placebo-controlled randomized trial showed. In the phase III study of over 500 patients undergoing standard induction and consolidation therapy, median overall survival (OS) […]
Healthcare Closely Watching FTC’s Proposed Ban on Non-Competes
A newly proposed rule from the Federal Trade Commission (FTC) that would ban non-compete clauses is being watched closely by the healthcare industry, already strained by staffing shortages and affected by changes in ownership structure even before the pandemic. The rule, if finalized after public comments are received for the next 2 months, would prevent […]
Why obesity is more dangerous for men: Building blocks of blood vessels found to be associated with inflammation and disease processes in male mice
A newly published study from York University sheds light on the biological underpinnings in sex differences in obesity-related disease, with researchers observing “striking” differences in the cells that build blood vessels in the fatty tissue of male versus female mice. Men are more likely than women to develop conditions associated with obesity such as cardiovascular […]
Opinion | Virtual Reality Can Help Get Our Patients Vaccinated
Whether it is the newly approved COVID-19 vaccines or school-required immunizations, many children receive their mandatory shots over summer vacation. Estimates show that as many as two-thirds of children and one-fourth of adults have strong fears around needles. Despite the past few years’ extensive coverage of the political and cultural objections to vaccinations, procedural anxiety […]
Researchers identify a new mechanism responsible for controlling auditory sensitivity
A new study published in PNAS highlights a newly identified mechanism of how auditory sensitivity is regulated that could temporarily reduce sensitivity of the auditory system to protect itself from loud sounds that can cause irreversible damage. The study, led by CU Anschutz researchers Andrew Mecca and Giusy Caprara in the laboratory of Anthony Peng, […]
As US obesity epidemic grows, new study shows who is gaining weight over the last decade
Newly published research from BYU exercise science researchers reveals critical, rare data detailing the severity of the obesity epidemic in the United States. The article, published in the Journal of Obesity, looked at the long-term weight gain of more than 13,800 U.S. adults — a rare data point unearthed in obesity research. They found that […]
Mental Health Issues Common, Often Overlooked in Prostate Cancer
NEW ORLEANS — More than a third of men with newly diagnosed prostate cancer had at least one mental health issue, which had a strong association with prior psychological wellbeing, a prospective cohort study showed. Almost 30% of the men had a fear of cancer recurrence or poor prognosis, and 22% met diagnostic criteria for […]
New Fermi arcs could provide a new path for electronics
Newly discovered Fermi arcs that can be controlled through magnetism could be the future of electronics based on electron spins. These new Fermi arcs were discovered by a team of researchers from Ames Laboratory and Iowa State University, as well as collaborators from the United States, Germany, and the United Kingdom. During their investigation of […]