If You Wake Up With A Stuffy Nose Every Day, Read This
Amazon A SinuCleanse Breathe neti pot, Arm & Hammer Simply Saline nasal rinse and a Honeywell humidifier. There are many unpleasant aspects of the cold winter season, and chief among them is the havoc it can wreak on sinuses. Even those who are not allergy-prone or actively sick can find themselves with never-ending nasal and […]
If You Wake Up With A Stuffy Nose Every Day, Read This
Amazon A SinuCleanse Breathe neti pot, Arm & Hammer Simply Saline nasal rinse and a Honeywell humidifier. There are many unpleasant aspects of the cold winter season, and chief among them is the havoc it can wreak on sinuses. Even those who are not allergy-prone or actively sick can find themselves with never-ending nasal and […]
The Most Common Flu Symptoms Doctors Are Seeing Right Now
Oscar Wong via Getty Images Fever, chills, muscle aches and nasal congestion are all among the commonly reported flu symptoms. With multiple respiratory viruses swirling this time of year, it can be hard to know which sickness you’re dealing with. But with cases of flu on the rise in much of the country, it’s important […]
Spravato Safety Holds Up Long-Term for Treatment-Resistant Depression
NASHVILLE — Esketamine nasal spray (Spravato) showed consistent long-term safety outcomes for patients with treatment-resistant depression (TRD), according to follow-up data from the SUSTAIN-3 trial. In the open-label, phase III study, intermittent dosing of esketamine for up to 6.5 years had a similar safety profile as dosing for up to 1 year, according to Reina […]
There’s 1 Huge Mistake People Make When Using Nasal Spray
vgajic via Getty Images Too many of us don’t know how to use nasal spray correctly, and it can hurt our sinuses in the long run. Whether it’s seasonal allergies, sinus infections or a cold, at some point, you are going to want to use a nasal spray to help out your stuffy, irritated nose. […]
Persistent Lymphadenopathy and Neck Abscesses in a Healthy Boy
What was causing this previously healthy 12-year-old boy to have nasal obstruction, increasing hoarseness and difficulty speaking, tender and swollen lymph nodes on his neck and recurring deep neck abscesses? That’s the question Samantha M. Moore, BS, of the Medical College of Wisconsin in Milwaukee, and colleagues tackled in a case reported in JAMA Otolaryngology–Head […]
Intranasal Zavegepant Shows Promise in Acute Migraine
Zavegepant, an investigational nasal spray formulation of a small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist, met its co-primary endpoints in a phase III randomized placebo-controlled trial of acute migraine. On both primary endpoints — 2-hour pain freedom (23.6% vs 14.9%, P<0.0001) and 2-hour freedom from most bothersome symptom (39.6% vs 31.1%, P=0.0012) — zavegepant was […]
In the NICU, High-Flow Oxygen Boosts Intubation Success on First Attempt
Incorporating nasal high-flow therapy during endotracheal intubation attempts in the neonatal intensive care unit (NICU) increased the chance of success on the first try, a randomized study found. In the SHINE trial of just over 250 intubation attempts at a pair of Australian NICUs, 50% of those that included high-flow therapy had a successful first […]
New COVID-19 nasal spray outperforms current antibody treatments in mice: A single inhaled dose treated or even prevented infection by COVID-19 and its variants
A new protein-based antiviral nasal spray developed by researchers at Northwestern University, University of Washington and Washington University at St. Louis is being advanced toward Phase I human clinical trials to treat COVID-19. Designed computationally and refined in the laboratory, the new protein therapies thwarted infection by interfering with the virus’ ability to enter cells. […]