MRI-Targeted Biopsy for Prostate Cancer Reduces Risk of Overdiagnosis
Excluding systematic biopsy in favor of MRI-targeted biopsy in men with elevated prostate-specific antigen (PSA) levels reduced the probability of detecting clinically insignificant cancers, but at the risk of missing some clinically significant cancers and delaying their diagnosis, the randomized GÖTEBORG-2 trial from Sweden showed. Among nearly 18,000 participants, 0.6% of men who underwent MRI-targeted […]
Novel Blood-Based Test Could Bolster MRI-Based Prostate Cancer Screening
Addition of a novel blood test to MRI-targeted biopsy in prostate cancer screening decreased overdetection while maintaining the ability to detect clinically significant cancer, Swedish researchers reported. They found that use of the test — called Stockholm3 — in a screening setting where MRI and targeted biopsies were used, performed at least as well as […]