Males born to obese mothers more likely to suffer health issues as adults
Males born to obese women are more likely to be overweight at birth and develop metabolic complications in later life, including liver disease and diabetes. The way that male sex hormones activate pathways in the developing liver is partly to blame. That’s the finding from a new study led by University of South Australia (UniSA) […]
This Is The Age You’re Happiest And Most Self-Confident
Warchi via Getty Images The older we get, the more content we feel. We know that wisdom comes with age ― and apparently so do a number of other joyful qualities. Research shows that the older you get, the more self-assured and content you are. In fact, those in their 60s are more likely to […]
Another Prostate Cancer Screening Candidate Outperforms Standard PSA Testing
SAN FRANCISCO — A multiparametric blood test for prostate cancer showed potential to avoid more than half of unnecessary biopsies without sacrificing accuracy, a large prospective study showed. In a comparison against the current PSA testing standard of ≥4 ng/mL, the Stockholm3 biomarker, which incorporates a PSA cutoff of 15 ng/mL with other proteins and […]
CAR-T Investigation: FDA Leaders Detail Decision on Cancer Risk Warning
The FDA has identified more cases of secondary T-cell malignancies following treatment with chimeric antigen receptor (CAR) T-cell therapies, cases that led the agency to demand new boxed warnings on approved agents in the class. With about 27,000 doses of the six B-cell maturation antigen (BCMA)- or CD19-directed CAR-T products having been administered in the […]
New Standard for Unresectable Hepatocellular Carcinoma?
SAN FRANCISCO — After more than 20 years of trying, systemic therapy for unresectable liver cancer has improved outcomes with transarterial chemoembolization (TACE), a randomized trial showed. Patients who received durvalumab (Imfinzi) plus bevacizumab (Avastin) in addition to TACE had a median progression-free survival (PFS) of 15.0 months as compared with 8.2 months for TACE […]
Want to Get More Healthcare Bills Passed? Fix the Filibuster, Suggests a Senator
WASHINGTON — The Senate could get a lot more done on healthcare and other issues if the rules for holding a filibuster were changed, a senator and his former chief of staff said Wednesday. “Think about, for example, drug prices, where 80% of Americans think every drug should be negotiated so we get the same […]
Multistate Licensure for Docs, Others Continues to Gain Steam
Efforts to sign up more states for “multistate compacts” that allow out-of-state physicians and other health professionals to practice in another state are continuing into 2024, experts say. For physicians, the ability to practice in multiple states has been simplified through the Interstate Medical Licensure Compact (IMLC), a project coordinated in part by the Federation […]
Co-Pays Hurt PrEP Use, Study Suggests
Higher out-of-pocket costs for HIV pre-exposure prophylaxis (PrEP) were projected to lead to more people discontinuing PrEP altogether in a new analysis, raising concerns about a possible rise in HIV infections. Risk-adjusted abandonment rates climbed from 5.5% among patients with no cost sharing to a projected 42.6% for patients with $500 out-of-pocket costs in a […]
Advanced Practice Providers Push to Unionize in Oregon
It’s not just physicians who are moving to unionize: More than 600 advanced practice providers (APPs) at the Oregon Health & Science University Hospital (OHSU) system have announced their intent to join a union. Members of the group include nurse practitioners (NPs), certified nurse midwives, and physician assistants (PAs), according to the Oregon Nurses Association […]
Early Bird? Night Owl? It May Matter for Eating Disorder Risk
People with anorexia nervosa may be more likely to be early risers, a genetic association study suggested. Looking at nearly 17,000 cases with this eating disorder, genetic liability for anorexia nervosa was associated with a more morning chronotype — or a preference for the morning (β=0.039, 95% CI 0.006-0.072, P=0.02), Hassan Dashti, PhD, RD, of […]