Weight-Loss Drug Benefit Spans HFpEF, HFmrEF
CLEVELAND — Semaglutide 2.4 mg (Wegovy) improved outcomes across the range of moderately reduced and preserved ejection fraction in heart failure (HFmrEF, HFpEF) related to obesity, a prespecified secondary analysis of the STEP-HFpEF trial showed. The benefits were consistent across subgroups, reported Javed Butler, MD, MPH, MBA, of the Baylor Scott and White Research Institute […]
Leptin helps hungry mice choose sex over food
To eat or to mate — that is the question (and the answer is: moderately hungry mice choose to mate). Researchers publishing in the journal Cell Metabolism on Thursday February 23 show that hungry mice prioritize interacting with members of the opposite sex over eating and drinking when their brains are stimulated with leptin, an […]
NAFLD Tied to Higher Risk of Heart Failure
Middle-age patients with non-alcoholic fatty liver disease (NAFLD) had a moderately higher risk of developing heart failure, an updated meta-analysis found. Pooled data on over 11 million participants showed NAFLD to be associated with a 50% greater risk of incident heart failure over a decade (pooled random-effects HR 1.50, 95% CI 1.34-1.67, P<0.0001), reported Giovanni […]
Benzodiazepines or Antihistamines for Acute Vertigo?
Moderately strong evidence suggested antihistamines provide greater acute vertigo relief than benzodiazepines, a meta-analysis showed. Single-dose antihistamines led to a 16.1-point (95% CI 7.2-25.0) greater decrease in vertigo symptom scores on a 100-point visual analog scale (VAS) compared with single-dose benzodiazepines at about 2 hours after treatment, reported Benton Hunter, MD, of Indiana University School […]
Reduced meat diet has many advantages: Study compares the impact of different diets on health, animal welfare and the environment
Which diet is better: moderately reduce meat consumption and eat more fruit, vegetables and wholegrain products, as recommended by the German Nutrition Society? Follow Germany’s southern neighbors’ example and eat more fish and seafood? Or even switch completely to a vegan diet? A new study by the University of Bonn (Germany) shows that the answer […]
CDC Panel Backs Third COVID Shot for the Immunocompromised
Moderately to severely immunocompromised people who received mRNA vaccines for COVID-19 should receive an additional dose, the CDC’s Advisory Committee on Immunization Practices (ACIP) said on Friday. In a unanimous 11-0 vote, the ACIP recommended an additional dose of the Pfizer (ages 12 and up) or Moderna vaccine (ages 18 and up) following a primary […]