Transapical Transcatheter Mitral Valve Replacement Trial Raises Questions
PHOENIX — Global experience with the novel Intrepid transapical transcatheter mitral valve replacement (TMVR) device through 2 years showed high risks of mortality and complications, raising concerns that might not be alleviated by the planned shift to a transfemoral approach. In the analysis pooling data from a pilot study and the APOLLO trial, the high-risk […]
Mitral Valve Repair Devices Go Head-to-Head, and the Top Spot Belongs to…
BOSTON — The Pascal device for edge-to-edge mitral valve repair was as safe and effective as the MitraClip device, the pivotal CLASP IID trial showed. In a pre-specified interim analysis of the first 180 patients enrolled, Pascal was non-inferior for the primary effectiveness endpoint of proportion of patients with mitral regurgitation no worse than 2+ […]
Researchers find benefits and drawbacks to two-step surgical approach for ‘leaky heart valves’: Study finds better short-term outcomes, but increased need for a pacemaker
Patients with mitral and tricuspid valve regurgitation, a condition sometimes called “leaky heart valves,” appeared to do better after two years if they had a tricuspid valve repair at the time of mitral valve surgery, according to a study supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes […]