Twelve-Month Data Back Pegloticase-Methotrexate Gout Combo
PHILADELPHIA — Previous findings that adding methotrexate to pegloticase (Krystexxa) in patients with gout was more effective than pegloticase alone have now been extended to a full year of treatment. At month 12 in the randomized, 152-patient MIRROR RCT trial, 60% of patients receiving the combination had serum urate levels below the target of 6 […]
Intravitreal Methotrexate Reduces Reoperation After Retinal Detachment Repair
NEW YORK CITY — Postoperative intravitreal methotrexate for retinal detachment led to a significant reduction in reoperation and improved visual acuity, a retrospective chart review showed. The absolute difference in reoperation rate was small, greater than 1% without methotrexate versus 0.4% with three to five postoperative injections of the antiproliferative agent, but the difference translated […]