Novel mechanism links genetic defect in IBD patients to gut leakiness: Study in mice and human tissue is the first to show how a disease mutation weakens barrier properties of epithelial cells lining the gut
A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier. The intestinal epithelium, a single layer of cells, plays […]
ivermectin (Stromectol): Generic, Uses, Side Effects, Interactions & Dosages
What is ivermectin, and how does it work (mechanism of action)? Ivermectin is an anti-parasitic medication. Ivermectin works by binding to invertebrate muscle and nerve cells of parasites, causing paralysis and death of parasites. Ivermectin is active against the non-adult form of Onchocerca volvulus. Ivermectin is also active against the intestinal activity of Strongyloides stercoralis. […]