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Introducing Allergenic Foods Early Tied to a Reduction in Later Allergies

Earlier introduction of common allergenic foods in the first year of life was linked to a lower risk of immunoglobulin E (IgE)-mediated food allergy from 1 to 5 years of age, according to a systematic review and meta-analysis of 23 randomized trials. Moderate-certainty evidence from four trials (n=3,295) showed that the introduction of multiple allergenic […]

Autopsies Show Relationship Between Alzheimer’s Pathology and Diet in Older Adults

Healthy, plant-based dietary patterns were linked with less postmortem Alzheimer’s disease pathology, primarily beta-amyloid load, in older adults. Both MIND diet scores (β -0.022, P=0.035; standardized beta -2.0) and Mediterranean diet scores (β -0.007, P=0.039; standardized beta -2.3) were significantly associated with lower global Alzheimer’s pathology, reported Puja Agarwal, PhD, of Rush University in Chicago, […]

Dementia Incidence Linked With Vitamin D Supplements

Vitamin D supplements were linked with lower dementia incidence and longer dementia-free survival, prospective data showed. In a sample of 12,000 older adults, exposure to vitamin D supplementation was associated with a 40% lower dementia incidence rate compared with no exposure (adjusted HR 0.60, 95% CI 0.55-0.65), reported Zahinoor Ismail, MD, of the University of […]

Better Cognition Even With Small Amounts of Physical Activity

Being and remaining physically active throughout adulthood was linked with higher cognition at age 69, a longitudinal cohort study showed. Effect sizes were similar across all adult ages, suggesting that being physically active at any time in adulthood — even as little as once a month — was tied to higher cognition, reported Sarah-Naomi James, […]

Phthalates Exposure Tied to Higher Incidence of Type 2 Diabetes in White Women

Exposure to phthalates — a type of endocrine-disrupting chemical — was linked with a higher incidence of type 2 diabetes among women, but only those who were white, researchers reported. In a study of over 1,300 women without diabetes, certain phthalate metabolites were associated with a higher incidence of diabetes during 6-year follow-up in a […]

Ultra-processed foods may be linked to increased risk of cancer

Higher consumption of ultra-processed foods may be linked to an increased risk of developing and dying from cancer, an Imperial College London-led observational study suggests. Researchers from Imperial’s School of Public Health have produced the most comprehensive assessment to date of the association between ultra-processed foods and the risk of developing cancers. Ultra-processed foods are […]

Midlife Cognition Linked With Moderate and Vigorous Physical Activity

Moderate and vigorous physical activity was linked with midlife cognition, a U.K. study showed. Among nearly 4,500 people born in 1970, time spent performing moderate and vigorous physical activity was associated with higher verbal memory and executive function scores relative to time spent sleeping, being sedentary, or engaging in light activity, according to John Mitchell, […]

IBD Risk Higher After Antibiotics

Antibiotics were linked with increased risk for inflammatory bowel disease (IBD), especially among individuals 40 or older, in a population-based study conducted in Denmark. Of more than 6 million individuals followed for approximately 19 years, antibiotic use was associated with nearly 50% increased incidence of IBD in people ages 40 to 60 (IRR 1.48, 95% […]

Scattered Brain Bleeds, Vasculitis in Alzheimer’s Trial Death

A fatal bleeding event in an Alzheimer’s clinical trial participant may have been linked with the investigational anti-amyloid agent lecanemab, a case report suggested. However, drug trialists are not willing to assign blame yet, especially as lecanemab’s fate hangs in a potential FDA approval for early Alzheimer’s disease later this week. Information about the case […]

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