Multi-Agent Treatment Offers Hope in Advanced or Recurrent Endometrial Cancer
MADRID — Immunotherapy, chemotherapy, and a PARP inhibitor in the first line improved progression-free survival (PFS) in patients with advanced or recurrent endometrial cancer, according to the DUO-E trial. The trial assessed the combination of durvalumab (Imfinzi) and platinum-based chemotherapy, followed by maintenance therapy with either durvalumab plus the PARP inhibitor olaparib (Lynparza) or durvalumab […]
Opinion | Learning From the Communications Failure
“What we’ve got here is failure to communicate.” In that classic line from the 1967 movie “Cool Hand Luke” starring Paul Newman, the warden (played by Strother Martin) points out that much better communication would keep things moving smoothly — or at least the way he wants them going. For all of us in healthcare, […]
Cronobacter Infection: How to Treat
Antibiotics are typically the first line of treatment for Cronobacter infections Cronobacter infections are often treated with antibiotics, typically cefazolin and amoxicillin, which are quite effective in most cases. However, treatment can be challenging because continued use of antibiotics can lead to the development of antibiotic resistance. What are the treatment options for Cronobacter infections? […]
Discovery offers starting point for better gene-editing tools
CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases. However, there is a last-mile problem — these tools need to be effectively delivered into every cell of the patient, and most Cas9s are too big to be fitted into […]
Researchers investigate role of gene associated with Alzheimer’s disease in brain’s immune cells
When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them. Researchers at Indiana University School of Medicine have been investigating how these immune cells in the brain — microglia — relate to a gene mutation recently found […]
Long Lines For COVID-19 Vaccine In Nairobi, Few Takers In Atlanta
NAIROBI, Kenya (AP) — Several hundred people line up every morning, starting before dawn, on a grassy area outside Nairobi’s largest hospital hoping to get the COVID-19 vaccine. Sometimes the line moves smoothly, while on other days, the staff tells them there’s nothing available, and they should come back tomorrow. Halfway around the world, at […]