8-hour time-restricted eating linked to a 91% higher risk of cardiovascular death
An analysis of over 20,000 U.S. adults found that people who limited their eating across less than 8 hours per day, a time-restricted eating plan, were more likely to die from cardiovascular disease compared to people who ate across 12-16 hours per day, according to preliminary research presented at the American Heart Association’s Epidemiology and […]
Low Tidal Volume Compliance Still Lacking in Mechanical Ventilation
Implementation of a well-established protective ventilation setting was limited in practice in the U.S. and U.K., electronic health records showed. From the records of mechanically ventilated people, median tidal volume was 7.48 mL/kg of predicted body weight in a U.K. database and 7.91 mL/kg in the U.S., both approaching the accepted upper limit of <8 […]
Lifestyle Factors and Glaucoma: Lots of Common Sense, Not So Much Evidence
SAN DIEGO — Limited data support a role for lifestyle factors in the prevention or management of glaucoma, according to a review presented here. Intuitively, diet, mental health, and good posture should contribute to good eye health, but the evidence does not support the intuition. Despite the dearth of positive studies, a better-safe-than-sorry approach remains […]
Sotatercept, Fixed-Dose Combo Therapy on the Right Path for PAH
NEW ORLEANS — The limited clinical evidence thus far supports investigational compounds for addition to or simplification of existing frontline therapies for pulmonary arterial hypertension (PAH), according to two trials presented here at the American College of Cardiology (ACC) annual meeting. The activin signaling inhibitor biologic sotatercept showed promise as an add-on to usual treatment […]
CDC: Monovalent Vax Has ‘Limited’ Protection Against BA.4/5 Hospitalization
A monovalent mRNA booster dose offered “limited” protection against COVID-related hospitalizations from the currently circulating Omicron variants, a CDC analysis found, likely due to the waning effects of the vaccines and potentially more immune evasion with BA.4/BA.5. In immunocompetent adults, vaccine effectiveness (VE) against hospitalization with three doses of mRNA vaccine dropped from 69% (95% […]
Rate of food insecurity skyrockets for Americans with cardiovascular disease: Diet is the greatest contributor to death from cardiovascular disease
The number of Americans with cardiovascular disease who are food insecure — having limited or uncertain access to adequate food — has skyrocketed over the last 20 years, a national study finds. A Michigan Medicine team analyzed data from the National Health and Nutrition Examination Survey representing 312 million American adults between 1999 and 2018, […]