Linaclotide Eases Abdominal Symptoms in IBS With Constipation
Linaclotide (Linzess) significantly alleviated abdominal symptoms in irritable bowel syndrome (IBS) patients with predominant constipation compared with placebo, researchers found in a randomized study. Using an abdominal score that averaged abdominal bloating, discomfort, and pain on an 11-point scale, the average overall change from baseline was -1.9 for patients treated with linaclotide and -1.2 for […]
A Gut-Wrenching Pandemic for Patients With Functional GI Issues
Patients with irritable bowel syndrome (IBS), gastroparesis, or functional dyspepsia had more gastrointestinal symptoms during the pandemic, a retrospective single-center study found. Compared to the 6 months before the pandemic, more patients with common functional gastrointestinal and motility disorders (FGIMD) experienced symptoms during the pandemic, including nausea or vomiting (16% vs 22%, respectively), constipation (13% […]