Novel Drug Cuts Proteinuria in APOL1-Mediated Kidney Disease
An investigative treatment targeting APOL1 activity significantly improved proteinuria APOL1-mediated kidney disease (AMKD), a proof-of-concept phase IIa study found. In a single-arm, open-label study, treatment with oral VX-147 — a small molecule acting as an APOL1 function inhibitor — significantly reduced urine protein to creatinine ratio (UPCR) by 47.6% (95% CI -60 to -31.3%) by […]
Counterfeit HIV Drugs; Turned Away By Rural EDs; Bogus Pop-Up Testing Sites
Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. Counterfeit HIV Drugs Drugmaker Gilead says a network of suppliers and distributors sold counterfeit versions of its HIV medications, the Wall Street Journal reported. The company found that just over 85,000 counterfeit bottles of Biktarvy and […]
Arthritis Drug Price Spiked 50-Fold; Who Is Monica Gandhi? Public Health in Crisis
Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. Arthritis Drug Price Spiked 50-Fold The cost of a 30-count box of indomethacin (Indocin), an anti-inflammatory rectal suppository for arthritis, surged from $198 in 2008 to more than $10,000 by October 1 of this year, according […]