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Out-of-Pocket Insulin Caps Boost Savings — But Not Insulin Use

While out-of-pocket caps on insulin indeed cut down on costs for commercially insured patients in the U.S., the policies didn’t do much to increase insulin use, claims data showed. After such policies were implemented in eight such states, insulin users under age 65 had a 17.4% (95% CI -23.9 to -10.9) relative reduction in costs […]

‘Alexa, Titrate My Insulin’: AI App Boosts Glycemic Control in Randomized Trial

A custom artificial intelligence (AI) app for insulin management advice helped patients with type 2 diabetes gain rapid glycemic control, a small randomized clinical trial found. In titrating basal insulin, those who used a voice-based conversational AI application — delivered over Amazon’s Alexa at home — more quickly achieved optimal insulin dosing (median 15 days […]

Comprehensive insulin signalling map shows interplay between genes and diet

Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a fundamental study of substantial importance. They say the authors share compelling evidence that sheds […]

Once-Weekly Insulin Icodec Bests Daily Insulin Options for Type 2 Diabetes

SAN DIEGO — Investigational once-weekly insulin icodec outperformed once-daily insulin glargine U100 when it came to glycemic control in type 2 diabetes, the phase IIIa ONWARDS 1 trial found. Over the course of 52 weeks, people with type 2 diabetes saw a greater average reduction in HbA1c with icodec compared with glargine U100 (estimated between-group […]

Is Electrical Duodenal Resurfacing the Next Big Thing for T2D and Obesity?

CHICAGO — A novel approach to revitalizing the duodenal mucosa as a means to restore normal insulin sensitivity in people with type 2 diabetes is showing strong promise in early studies, according to results presented here. In two single-arm trials of a system called ReCET, reported at Digestive Disease Week (DDW), patients with either poorly […]

Why Does Insulin Cost So Much? Big Pharma Isn’t the Only Player Driving Prices

Eli Lilly & Co.’s announcement that it is slashing prices for its major insulin products could make life easier for some diabetes patients while easing pressure on Big Pharma. It also casts light on the profiteering methods of the drug industry’s price mediators — the pharmacy benefit managers (PBMs) — at a time when Congress […]

Let’s Make Insulin More Affordable for All Who Need It, Biden Says

VIRGINIA BEACH, Va. — The U.S. needs to “finish the job” and make insulin more affordable for everyone who needs it, President Biden said here Tuesday. “We capped the cost of insulin at $35 a month for seniors on Medicare,” said Biden, who spoke at the Kempsville Recreation Center. “When I introduced it, it was […]

GOP Objections Kill Proposed Cap On Insulin Costs In Private Insurance

A proposal to cap insulin costs for people with private insurance won’t be part of the sweeping climate and health care legislation that Senate Democrats are about to pass after Republicans moved to strip it out of the bill on Sunday. The Democratic proposal needed 60 votes to survive, but only seven Republicans joined the […]

Nanotherapy offers new hope for the treatment of Type 1 diabetes

Individuals living with Type 1 diabetes must carefully follow prescribed insulin regimens every day, receiving injections of the hormone via syringe, insulin pump or some other device. And without viable long-term treatments, this course of treatment is a lifelong sentence. Pancreatic islets control insulin production when blood sugar levels change, and in Type 1 diabetes, […]

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