Dupilumab Cuts Lung Inflammation, Breaks Up Mucus Plugs in Asthma Patients
WASHINGTON — Dupilumab (Dupixent) reduced airway inflammation and increased lung capacity in patients with uncontrolled, moderate-to-severe asthma, while also reducing troublesome mucus plugs, a multinational postmarketing study showed. In the randomized study, treatment with dupilumab led to significant reductions in airway inflammation at 24 weeks, with 57% achieving a fractional exhaled nitric oxide (FeNO) level […]
How fasting may protect against inflammation
Cambridge scientists may have discovered a new way in which fasting helps reduce inflammation — a potentially damaging side-effect of the body’s immune system that underlies a number of chronic diseases. In research published in Cell Reports, the team describes how fasting raises levels of a chemical in the blood known as arachidonic acid, which […]
Common Headaches May Be Pains in the Neck
CHICAGO — Inflammation and edema of the trapezius muscles appeared linked to tension and migraine headaches, a small prospective cohort study found. Patients with mixed-type tension and migraine headaches demonstrated the highest muscle T2 MRI values (31.4 ms on the right and left sides), and the average value was significantly higher compared to those with […]
Is red meat intake linked to inflammation?
Inflammation is a risk factor for many chronic diseases, including cardiovascular disease (CVD), and the impact of diet on inflammation is an area of growing scientific interest. In particular, recommendations to limit red meat consumption are often based, in part, on old studies suggesting that red meat negatively affects inflammation — yet more recent studies […]
New research adds evidence to the benefits of ginger supplements for treating autoimmune diseases
New research has revealed a potentially important role ginger supplements can play in controlling inflammation for people living with autoimmune diseases. The research published today in JCI Insight focused on studying the impact of ginger supplementation on a type of white blood cell called the neutrophil. The study was especially interested in neutrophil extracellular trap […]
Scientists link genes to diet in inflammatory bowel disease: A study in mice identifies candidate genes associated with bowel inflammation caused by a high-fat diet
A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans. The findings are published as a Reviewed Preprint in eLife. Described by the editors as a fundamental study, the work provides a framework for […]
IBD and Preterm Birth Risk; Leprosy Bacteria Promote Liver Growth; COVID and IBD
Histological inflammation and clinical disease activity in inflammatory bowel disease (IBD) were risk factors for preterm birth, especially in the case of ulcerative colitis. (eClinicalMedicine) Leprosy-causing bacteria (Mycobacterium leprae) promoted growth in healthy liver tissue in armadillos and may be able to help renew aging or injured livers. (Cell Reports Medicine) For older IBD patients […]
High-fat diets trigger inflammatory immune cell generation in bone: A study suggests that high-fat diets fuel the creation of inflammatory immune cells in the bone marrow of mice.
The results may help explain how high-fat diets trigger inflammation, which can contribute to the development of insulin resistance, type 2 diabetes and other complications in individuals with obesity. An invasion of inflammatory immune cells, called monocytes, into fat tissue is a hallmark of obesity, but what leads to this harmful phenomenon is unclear. Many […]
Anti-inflammatory compound shows potential in treating patients with severe COVID-19
An anti-inflammatory compound may have the potential to treat systemic inflammation and brain injury in patients with severe COVID-19 and significantly reduce their chances of death, according to a new study from UTHealth Houston and other institutions. A team of researchers including UTHealth Houston faculty members Aaron M. Gusdon, MD, assistant professor in the Vivian […]
How Long Can a Person Live after Being Diagnosed with Hep C?
Hepatitis is inflammation of the liver. There are a variety of toxins, diseases, illicit drugs, medications, bacterial and viral infections, and heavy alcohol use can case inflammation of the liver. Hepatitis C viral infection (HCV) is one type of hepatitis. According to the CDC, in 2014 there were an estimated 30,500 cases of acute hepatitis […]